Detailed information NTG0131106

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: NG74_RS16620
• Genome accession: NZ_CP009679
• Coordinates: 3463954..3465117 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain JS25R
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3458954..3470117

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NG74_RS16590 (NG74_03435)	-	3459219..3459638 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
NG74_RS16595 (NG74_03436)	comFC	3459712..3460401 (-)	690	WP_197538213.1	ComF family protein	Machinery gene
NG74_RS16600 (NG74_03437)	-	3460407..3460691 (-)	285	WP_022553866.1	late competence development ComFB family protein	-
NG74_RS16605 (NG74_03438)	comFA	3460749..3462134 (-)	1386	WP_022553867.1	DEAD/DEAH box helicase	Machinery gene
NG74_RS16610 (NG74_03439)	-	3462242..3463090 (-)	849	WP_003151387.1	DegV family protein	-
NG74_RS16615 (NG74_03440)	degU	3463188..3463877 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
NG74_RS16620 (NG74_03441)	degS	3463954..3465117 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
NG74_RS16625 (NG74_03442)	-	3465340..3465987 (+)	648	WP_007407485.1	YigZ family protein	-
NG74_RS16630 (NG74_03443)	-	3465992..3467206 (+)	1215	WP_022553868.1	LCP family protein	-
NG74_RS16635 (NG74_03444)	-	3467306..3468382 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
NG74_RS16640 (NG74_03445)	tuaH	3468514..3469710 (-)	1197	WP_022553869.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=131106 NG74_RS16620 WP_007407484.1 3463954..3465117(-) (degS) [Bacillus velezensis strain JS25R]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=131106 NG74_RS16620 WP_007407484.1 3463954..3465117(-) (degS) [Bacillus velezensis strain JS25R]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951