Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   VT05_RS00775 Genome accession   NZ_CP012026
Coordinates   144913..147204 (-) Length   763 a.a.
NCBI ID   WP_003694941.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain FA19     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 139913..152204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VT05_RS16290 - 140321..141543 (+) 1223 Protein_148 restriction endonuclease subunit S -
  VT05_RS00770 (VT05_00152) - 141775..144873 (+) 3099 WP_003692800.1 type I restriction endonuclease subunit R -
  VT05_RS00775 (VT05_00153) clpC 144913..147204 (-) 2292 WP_003694941.1 ATP-dependent Clp protease ATP-binding subunit ClpA Regulator
  VT05_RS00780 (VT05_00154) clpS 147206..147508 (-) 303 WP_010951037.1 ATP-dependent Clp protease adapter ClpS -
  VT05_RS00785 (VT05_00155) - 147753..147956 (+) 204 WP_002217533.1 cold-shock protein -
  VT05_RS00790 (VT05_00156) pmbA 148255..149586 (-) 1332 WP_003687847.1 metalloprotease PmbA -
  VT05_RS00795 (VT05_00157) yjgA 149740..150246 (+) 507 WP_020996793.1 ribosome biogenesis factor YjgA -
  VT05_RS00800 (VT05_00158) - 150293..151024 (+) 732 WP_003687850.1 hypothetical protein -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84345.22 Da        Isoelectric Point: 6.6057

>NTDB_id=130764 VT05_RS00775 WP_003694941.1 144913..147204(-) (clpC) [Neisseria gonorrhoeae strain FA19]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDAAVPNVLKLCGADLKAVSEQLAASVAENTPLIPDHLLDTVET
RPTLGFQRVIQRAMVHTQSAGKGLAEPLDVLVALMSETDSHAVYFLKLQSVTRFEVLRCIAHGSPDEDEDDGNYFSDGMD
DDNENRTKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALADGLAHQIVNDD
IPDALKEAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTGGGTMDASNLLKPALAKGS
LRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVAETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERFLP
DKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLGRDLNNMVYGQEDAIDALVSAVK
MSRSGLGLPDKPIGSFLFSGPTGVGKTEVAKQLAYSMGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNK
QPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKRERGDEMQAINKL
FTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHRLLDKKVEAEFTPALRKYLAEKGFDPQMGARPMHRLIQEKIRKP
LADELLFGKLADGGFVRIDWDAAKEEAVLKFKKSKVKIKTASA

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=130764 VT05_RS00775 WP_003694941.1 144913..147204(-) (clpC) [Neisseria gonorrhoeae strain FA19]
ATGCTTGCCCCTGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCGCCGTGCCGAACGTCTTAAAACTCTGCGGTGCGGATTTAAAAG
CGGTGTCCGAACAACTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGACCACCTTTTAGACACGGTCGAAACC
CGGCCCACGCTCGGCTTCCAACGCGTCATCCAGCGGGCGATGGTGCATACCCAATCGGCAGGCAAAGGCTTGGCCGAGCC
TTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACGCCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGACGATGGCAACTATTTTTCAGACGGCATGGAC
GACGATAATGAGAACCGCACCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGTCAAAGC
CGGCCGTATCGATCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTGTGCCGCCGCCGCAAAAACA
ATCCGCTTTTGGTCGGCGAAGCAGGCGTGGGCAAAACCGCGCTGGCGGACGGTTTGGCACATCAAATCGTCAACGACGAC
ATTCCCGACGCGCTCAAAGAGGCCGAAGTGTACGCGCTGGATATGGGTTCGCTTTTGGCGGGCACAAAATACCGCGGCGA
CTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTATTCATCGACGAAATCCACA
CCATCATCGGCGCGGGCAGCACCGGCGGCGGCACGATGGACGCGTCCAACCTGCTCAAACCCGCATTGGCGAAAGGTTCA
TTGCGCTGTATCGGCGCAACCACTTACGACGAATACCGTACTATTTTTGACAAAGACCACGCCCTAAGCCGCCGCTTCCA
GAAAATCGACGTGGTCGAACCCACCGTTGCCGAAACCGTTCAAATCCTGCGCGGCTTGAAACCGATGTTCGAAGCCTTCC
ACCAAGTCCGCTACACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCCCGCTACATCAACGAGCGCTTCCTGCCC
GACAAAGCCATCGACGTAATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGTCATCGG
CAAAGCGCAAATCGAAACCGTCATCGCCAAAGTCGCGCGGATTCCCGAAAAGACCGTGTCGCACGACGACAAACAAGTGT
TGCAATTCCTCGGCCGCGATTTGAACAATATGGTTTACGGGCAGGAAGACGCCATCGACGCGCTGGTTTCCGCCGTCAAA
ATGTCGCGTTCGGGCTTGGGGCTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCTACCGGCGTCGGCAAAAC
CGAAGTCGCCAAACAGCTTGCCTACTCAATGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCACG
CCGTATCGCGACTCATCGGCGCGCCACCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAG
CAGCCTCATTGCGTGTTGCTCTTGGACGAAATCGAAAAAGCCCATCCAGATATTTTCAACGTCCTCCTGCAAGTCATGGA
CGCAGGCAAACTGACCGATAACAACGGTAAGAGCGCCGATTTCCGCAACGTCATCCTGATCATGACCACCAACGCAGGCG
CAGAAAGCCTCAGCCGACCCAGCCTAGGCTTTACCGCCAAACGCGAGCGCGGCGACGAAATGCAGGCAATCAACAAACTC
TTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATCATCCCGTTTGCACCTTTGTCCGAACCCATCATCGTCAAAGTCGT
GGACAAATTCCTGCTCCAGCTCGAACACCGGCTCCTCGACAAAAAAGTCGAAGCCGAATTCACACCGGCATTGCGTAAAT
ACTTGGCAGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGCAAACCG
CTCGCCGACGAACTCCTGTTCGGCAAACTCGCCGACGGCGGCTTTGTGCGGATAGACTGGGATGCGGCGAAAGAAGAAGC
CGTATTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCTCCGCATAA

Domains

Predicted by InterProScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-61)

AAA lid domain (AAA_lid_9)

(356-452)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(658-738)

ATPase family associated with various cellular activities (AAA) (AAA)

(216-348)

AAA domain (Cdc48 subfamily) (AAA_2)

(491-652)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

37.881

100

0.408
  clpC Streptococcus mutans UA159

38.308

100

0.404
  clpC Bacillus subtilis subsp. subtilis str. 168

37.345

100

0.394
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

41.586

94.233

0.392

Multiple sequence alignment