Detailed information NTG0130042

Bioinformatically predicted

Overview

• Name: letA
• Type: Regulator
• Locus tag: PA50071_RS12060
• Genome accession: NZ_CP012001
• Coordinates: 2570979..2571623 (+)
• Length: 214 a.a.
• NCBI ID: WP_003090351.1
• Uniprot ID: A0A0H2ZC55
• Organism: Pseudomonas aeruginosa DSM 50071 = NBRC 12689 strain DSM 50071
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2565979..2576623

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PA50071_RS12045 (PA50071_12055)	-	2566613..2567827 (+)	1215	WP_003113355.1	MFS transporter	-
PA50071_RS12050 (PA50071_12060)	-	2567843..2568871 (-)	1029	WP_003097554.1	AraC family transcriptional regulator	-
PA50071_RS12055 (PA50071_12065)	pqsH	2569489..2570637 (+)	1149	WP_003090354.1	2-heptyl-3-hydroxy-4(1H)-quinolone synthase	-
PA50071_RS12060 (PA50071_12070)	letA	2570979..2571623 (+)	645	WP_003090351.1	UvrY/SirA/GacA family response regulator transcription factor	Regulator
PA50071_RS12065 (PA50071_12075)	uvrC	2571624..2573450 (+)	1827	WP_003097551.1	excinuclease ABC subunit UvrC	-
PA50071_RS12070 (PA50071_12080)	pgsA	2573484..2574044 (+)	561	WP_003090349.1	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 23608.53 Da
• Isoelectric Point: 6.1073

>NTDB_id=130042 PA50071_RS12060 WP_003090351.1 2570979..2571623(+) (letA) [Pseudomonas aeruginosa DSM 50071 = NBRC 12689 strain DSM 50071]
MIKVLVVDDHDLVRTGITRMLADIEGLQVVGQADCGEDCLKLARELKPDVVLMDVKMPGIGGLEATRKLLRSQPDIKVVV
VTVCEEDPFPTRLMQAGAAGYMTKGAGLEEMVQAIRQVFAGQRYISPQIAQQLALKSFQPQQHDSPFDSLSEREIQIALM
IANCHKVQSISDKLCLSPKTVNTYRYRIFEKLSITSDVELALLAVRHGMVDAAS

Nucleotide

• Length: 645 bp

>NTDB_id=130042 PA50071_RS12060 WP_003090351.1 2570979..2571623(+) (letA) [Pseudomonas aeruginosa DSM 50071 = NBRC 12689 strain DSM 50071]
GTGATTAAGGTGCTGGTGGTCGACGACCACGATCTGGTACGCACCGGTATTACCCGCATGCTGGCCGACATCGAAGGCTT
GCAAGTGGTCGGCCAGGCCGACTGCGGTGAAGACTGTCTGAAACTGGCCCGCGAACTGAAGCCGGATGTCGTCCTGATGG
ACGTGAAGATGCCCGGTATCGGCGGCCTGGAGGCAACCCGCAAGCTGCTGCGCAGCCAGCCCGACATCAAGGTCGTGGTA
GTCACCGTCTGCGAAGAGGATCCGTTCCCCACCCGCCTCATGCAGGCCGGCGCCGCCGGCTACATGACCAAGGGCGCGGG
GCTGGAGGAAATGGTCCAGGCGATTCGCCAGGTCTTCGCCGGCCAGCGCTATATCAGCCCGCAGATCGCCCAGCAACTGG
CGCTGAAGTCCTTCCAGCCGCAGCAGCACGATTCCCCCTTCGATTCGCTGTCCGAGCGCGAGATCCAGATCGCCCTGATG
ATCGCCAACTGCCACAAGGTGCAGAGCATCTCCGACAAGCTGTGCCTGTCGCCGAAGACCGTGAATACCTATCGCTACCG
CATCTTCGAGAAGCTCTCGATCACCAGCGACGTGGAGCTGGCGCTGCTCGCCGTCCGCCACGGCATGGTCGATGCCGCCA
GCTAG

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, luxR family (GerE) (148-204)

• Response regulator receiver domain (Response_reg) (4-116)

3D structure

• AlphaFold DB: A0A0H2ZC55

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letA	Legionella pneumophila str. Paris	54.502	98.598	0.537
letA	Legionella pneumophila strain ERS1305867	54.502	98.598	0.537