Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABU16_RS00700 Genome accession   NZ_CP011882
Coordinates   134023..134658 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain TO-A JPC     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 129023..139658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABU16_RS00680 (ABU16_0141) yvzF 130080..130265 (-) 186 WP_003244599.1 YvzF family protein -
  ABU16_RS00685 (ABU16_0142) gerAA 130383..131831 (+) 1449 WP_048217611.1 spore germination receptor protein GerAA -
  ABU16_RS00690 (ABU16_0143) gerAB 131800..132897 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  ABU16_RS00695 (ABU16_0144) gerAC 132894..134015 (+) 1122 WP_003243203.1 spore germination receptor protein GerAC -
  ABU16_RS00700 (ABU16_0145) vraR 134023..134658 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  ABU16_RS00705 (ABU16_0146) liaS 134636..135718 (-) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  ABU16_RS00710 (ABU16_0147) liaF 135715..136440 (-) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  ABU16_RS00715 (ABU16_0148) liaG 136474..137346 (-) 873 WP_003244420.1 DUF4097 domain-containing protein -
  ABU16_RS00720 (ABU16_0149) liaH 137447..138124 (-) 678 WP_003243047.1 PspA/IM30 family protein -
  ABU16_RS00725 (ABU16_0150) liaI 138151..138531 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=129536 ABU16_RS00700 WP_003243201.1 134023..134658(-) (vraR) [Bacillus subtilis strain TO-A JPC]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=129536 ABU16_RS00700 WP_003243201.1 134023..134658(-) (vraR) [Bacillus subtilis strain TO-A JPC]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408

Multiple sequence alignment