Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   M444_RS31880 Genome accession   NZ_CP011664
Coordinates   7362863..7363528 (+) Length   221 a.a.
NCBI ID   WP_037798931.1    Uniprot ID   -
Organism   Streptomyces sp. Mg1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7357863..7368528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M444_RS31860 (M444_31845) - 7359847..7360701 (-) 855 WP_053065840.1 hypothetical protein -
  M444_RS31865 (M444_31850) - 7360780..7361148 (-) 369 WP_037798923.1 DUF4180 domain-containing protein -
  M444_RS31870 (M444_31855) - 7361218..7361550 (-) 333 WP_037798924.1 hypothetical protein -
  M444_RS31875 (M444_31860) - 7361658..7362866 (+) 1209 WP_037798928.1 sensor histidine kinase -
  M444_RS31880 (M444_31865) vraR 7362863..7363528 (+) 666 WP_037798931.1 response regulator transcription factor Regulator
  M444_RS31885 (M444_31870) - 7363680..7363997 (+) 318 WP_037800254.1 SHOCT domain-containing protein -
  M444_RS31890 (M444_31875) - 7364073..7365236 (+) 1164 WP_200911934.1 aminotransferase class V-fold PLP-dependent enzyme -
  M444_RS31895 (M444_31880) - 7365333..7365947 (+) 615 WP_037798935.1 TetR/AcrR family transcriptional regulator -
  M444_RS31900 (M444_31885) - 7365931..7367565 (+) 1635 WP_037798937.1 isovaleryl-CoA dehydrogenase -
  M444_RS31905 (M444_31890) - 7367592..7367891 (-) 300 WP_037798939.1 hypothetical protein -
  M444_RS31910 (M444_31895) - 7367884..7368177 (-) 294 WP_037798940.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23688.59 Da        Isoelectric Point: 5.4402

>NTDB_id=129208 M444_RS31880 WP_037798931.1 7362863..7363528(+) (vraR) [Streptomyces sp. Mg1]
MIRVLLADDQQLVRAGFRALLDAQPDIEVAGEAADGAEALRLVRALRPDIALMDIRMPGLDGLAATRAITGDAALTSVKV
VMLTTFDLDEYVFEAIRSGACGFLVKDTEPEELLRAVRAVVAGDALLSPGVTRRLIAEFAARSKAPAAAAGLERLTDRER
EVMALVGMGMSNEEIARRLVVSPLTAKTHVSRTMIKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=129208 M444_RS31880 WP_037798931.1 7362863..7363528(+) (vraR) [Streptomyces sp. Mg1]
GTGATCCGCGTACTGCTCGCCGACGACCAGCAACTGGTCCGGGCCGGCTTCCGGGCGCTCCTCGACGCGCAGCCCGACAT
CGAGGTGGCGGGCGAGGCCGCCGACGGCGCCGAGGCCCTGCGCCTGGTCCGCGCCCTGCGCCCCGACATCGCCCTCATGG
ACATCCGGATGCCCGGGCTCGACGGTCTGGCCGCCACCCGCGCGATCACCGGGGACGCCGCGCTGACCTCGGTCAAGGTG
GTCATGCTGACCACCTTCGACCTCGACGAGTACGTCTTCGAGGCCATCCGCTCCGGCGCCTGCGGCTTCCTCGTCAAGGA
CACCGAACCGGAGGAACTGCTGCGCGCGGTACGGGCGGTGGTCGCGGGGGACGCCCTGCTCTCGCCCGGGGTGACGCGCC
GGCTGATCGCCGAGTTCGCGGCCCGCTCGAAGGCCCCCGCGGCCGCGGCCGGGCTGGAACGGCTGACCGACCGGGAGCGC
GAGGTGATGGCCCTGGTGGGCATGGGGATGTCCAACGAGGAGATCGCCCGCCGCCTGGTGGTCAGCCCGCTGACAGCGAA
GACGCACGTCAGCCGGACGATGATCAAGCTCGGGGCCCGGGACCGGGCCCAACTGGTGGTGCTGGCGTACGAGTCCGGGC
TGGTGCGCCCCGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.674

97.285

0.367
  degU Bacillus subtilis subsp. subtilis str. 168

35.556

100

0.362

Multiple sequence alignment