Detailed information NTG0129202

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: LG33_RS14940
• Genome accession: NZ_CP009423
• Coordinates: 2801078..2801965 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain USA300_SUR1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2796078..2806965

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LG33_RS14905 (LG33_14695)	-	2796097..2796189 (+)	93	WP_010956583.1	hypothetical protein	-
LG33_RS14910 (LG33_14700)	-	2796297..2796794 (-)	498	WP_001065268.1	glutathione peroxidase	-
LG33_RS14915 (LG33_14705)	-	2796804..2797064 (-)	261	WP_001789910.1	hypothetical protein	-
LG33_RS14925 (LG33_14710)	-	2797446..2797559 (-)	114	WP_001791776.1	hypothetical protein	-
LG33_RS14930 (LG33_14720)	-	2798218..2800218 (-)	2001	WP_000776751.1	ABC transporter permease	-
LG33_RS14935 (LG33_14725)	-	2800215..2800970 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
LG33_RS14940 (LG33_14730)	braS	2801078..2801965 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
LG33_RS14945 (LG33_14735)	braR	2801976..2802641 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
LG33_RS14950 (LG33_14740)	-	2802667..2802867 (-)	201	WP_000604728.1	hypothetical protein	-
LG33_RS14955 (LG33_14750)	-	2803065..2804489 (+)	1425	WP_000953744.1	alkaline phosphatase	-
LG33_RS16090	-	2804549..2804650 (-)	102	WP_000731972.1	SE2200 family small protein	-
LG33_RS14965 (LG33_14760)	-	2804772..2805227 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
LG33_RS14970 (LG33_14765)	-	2805472..2806233 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=129202 LG33_RS14940 WP_000143419.1 2801078..2801965(-) (braS) [Staphylococcus aureus strain USA300_SUR1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=129202 LG33_RS14940 WP_000143419.1 2801078..2801965(-) (braS) [Staphylococcus aureus strain USA300_SUR1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997