Detailed information NTG0129174

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: M444_RS19820
• Genome accession: NZ_CP011664
• Coordinates: 4582185..4583309 (-)
• Length: 374 a.a.
• NCBI ID: WP_008743311.1
• Uniprot ID: A0ABZ1RK95
• Organism: Streptomyces sp. Mg1
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4577185..4588309

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M444_RS19790 (M444_19770)	cseB	4577400..4578107 (-)	708	WP_008743305.1	two-component system response regulator CseB	-
M444_RS19795 (M444_19775)	-	4578147..4578797 (-)	651	WP_008743306.1	hypothetical protein	-
M444_RS19800 (M444_19780)	-	4578836..4579396 (-)	561	WP_037794920.1	SigE family RNA polymerase sigma factor	-
M444_RS19805 (M444_19785)	-	4579582..4580520 (-)	939	WP_008743308.1	A/G-specific adenine glycosylase	-
M444_RS19810 (M444_19790)	-	4580517..4581158 (-)	642	WP_047960648.1	phosphatase PAP2 family protein	-
M444_RS19815 (M444_19795)	-	4581319..4582137 (+)	819	WP_050779411.1	hypothetical protein	-
M444_RS19820 (M444_19800)	disA	4582185..4583309 (-)	1125	WP_008743311.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
M444_RS19825 (M444_19805)	radA/sms	4583459..4584874 (-)	1416	WP_008743312.1	DNA repair protein RadA	Machinery gene
M444_RS19830 (M444_19810)	-	4585042..4586877 (+)	1836	WP_047960650.1	sigma-70 family RNA polymerase sigma factor	-
M444_RS19835 (M444_19815)	-	4586898..4587704 (-)	807	WP_008743314.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40320.32 Da
• Isoelectric Point: 5.0226

>NTDB_id=129174 M444_RS19820 WP_008743311.1 4582185..4583309(-) (disA) [Streptomyces sp. Mg1]
MAAKDGAAASGKSGASSKQEAMMRASLSAVAPGQPLRDGLERIVRGNTGGLIVLGMDKSVEAMCTGGFVLDVEFTATRLR
ELCKLDGALIIDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVVSVSQSMRLIALYVDGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVDEALPALDALTHPELLELAIVAKALGYTGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=129174 M444_RS19820 WP_008743311.1 4582185..4583309(-) (disA) [Streptomyces sp. Mg1]
GTGGCAGCCAAGGACGGGGCAGCAGCATCCGGCAAGTCGGGAGCGAGCTCCAAGCAGGAGGCCATGATGCGTGCCTCGCT
GAGCGCGGTCGCACCTGGTCAGCCGCTGCGTGACGGCCTGGAACGGATCGTTCGCGGCAACACCGGCGGGCTGATCGTCC
TCGGGATGGACAAGTCCGTCGAGGCGATGTGTACCGGCGGTTTCGTGCTGGACGTGGAGTTCACCGCGACGCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGCGCTGATCATCGACAAGGACATCACCAAGATCCTGCGGGCGGGGGTGCAGCTCGTCCC
CGACGCGTCGATCCCGACGGAGGAGACGGGCACGCGGCACCGGACCGCCGACCGGGTCTCGAAGCAGTGCGGGTTCCCCG
TCGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGGCGCGTGCTGGAGGAGTCGGGGGCG
ATCCTGTCCCGGGCGAACCAGGCGCTCGCGACGCTGGAGCGGTACAAGCTGCGGCTCGACGAGGTCGCGGGGACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTCACGGTGCGCGACGTGACGGCGGTCGCGCAGCGGCTGGAAATGGTTCGCCGGATCG
CGACGGAGATCGCGGAGTACGTGGTCGAGCTGGGCACGGACGGGCGACTGCTCTCCCTCCAGCTGGACGAGCTGACGGTG
GGCATCGAGCAGGAACGCGAGCTGGTCATCCGGGACTACGTGCCGGAGCCGACGGCGAAGCGGTCGCGGACGGTGGACGA
GGCGCTGCCGGCGCTGGACGCGCTGACGCATCCGGAGCTGCTGGAACTGGCCATCGTCGCGAAGGCGCTGGGGTACACGG
GTTCGCCGGAGACCCTGGACTCGGCGGTGTCCCCGCGGGGCTACCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGGGCC
ATCATCGAGCGGCTGGTGGAGCACTTCGGGGGCCTGCAGAAGCTGCTGGCGGCGTCGGTGGACGACCTCCAGACCGTGGA
CGGCGTCGGCGAGGCCCGTGCGCGCAGCGTCCGCGAGGGCCTGTCCCGCCTGGCGGAATCCTCGATCCTGGAACGCTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.706	96.524	0.441