Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   M444_RS09400 Genome accession   NZ_CP011664
Coordinates   2242433..2243083 (-) Length   216 a.a.
NCBI ID   WP_008743867.1    Uniprot ID   -
Organism   Streptomyces sp. Mg1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2237433..2248083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M444_RS09370 (M444_09355) - 2237790..2238566 (-) 777 WP_199781103.1 sulfite exporter TauE/SafE family protein -
  M444_RS09375 (M444_09360) - 2238656..2239624 (-) 969 WP_008743861.1 SPFH domain-containing protein -
  M444_RS09380 (M444_09365) - 2239729..2240157 (-) 429 WP_008743862.1 NfeD family protein -
  M444_RS09385 (M444_09370) - 2240233..2241027 (-) 795 WP_008743863.1 ABC transporter ATP-binding protein -
  M444_RS09390 (M444_09375) - 2241173..2241955 (+) 783 WP_008743864.1 hypothetical protein -
  M444_RS09395 (M444_09380) - 2242045..2242281 (-) 237 WP_008743866.1 chaplin -
  M444_RS09400 (M444_09385) vraR 2242433..2243083 (-) 651 WP_008743867.1 response regulator transcription factor Regulator
  M444_RS09405 (M444_09390) - 2243076..2244206 (-) 1131 WP_008743868.1 GAF domain-containing sensor histidine kinase -
  M444_RS42965 (M444_09395) - 2244365..2244748 (+) 384 Protein_1906 SDR family NAD(P)-dependent oxidoreductase -
  M444_RS39730 (M444_09400) - 2244745..2245520 (+) 776 Protein_1907 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  M444_RS09420 (M444_09405) - 2245834..2246505 (+) 672 WP_037795410.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23472.70 Da        Isoelectric Point: 5.3701

>NTDB_id=129144 M444_RS09400 WP_008743867.1 2242433..2243083(-) (vraR) [Streptomyces sp. Mg1]
MADTPGRVRVLLVDDHQVVRRGLRTFLEVQEDIEVVGEASDGEEGIARAEELRPDVILMDIKMPGTDGIEALRRLRELAN
PARVLIVTSFTEQRTVVPALRAGAAGYVYKDIDPDALAGAIRSVHAGHVLLQPEVAVALLTQDDQGPSSSRGGALTDRER
EVLSHIADGRSNREIARALVLSEKTVKTHVSNILMKLDVADRTQAALWAVRHGIGD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=129144 M444_RS09400 WP_008743867.1 2242433..2243083(-) (vraR) [Streptomyces sp. Mg1]
GTGGCTGACACACCCGGCAGGGTCCGCGTACTGCTCGTCGACGACCACCAGGTGGTCCGGCGCGGGCTGCGCACCTTCCT
GGAGGTGCAGGAGGACATCGAGGTGGTCGGCGAGGCCTCGGACGGCGAGGAGGGCATCGCCCGCGCCGAGGAACTGCGGC
CCGACGTGATCCTGATGGACATCAAGATGCCCGGCACCGACGGCATCGAGGCGCTGCGGCGGCTTCGGGAGCTGGCGAAC
CCGGCGCGCGTGCTGATCGTCACCAGCTTCACCGAGCAGCGGACGGTGGTCCCCGCGCTGCGGGCCGGCGCCGCCGGGTA
CGTCTACAAGGACATCGACCCCGACGCCCTGGCCGGGGCCATCCGCTCGGTGCACGCGGGCCACGTCCTGCTCCAGCCGG
AGGTGGCGGTGGCCCTGCTCACGCAGGACGACCAGGGCCCGTCGTCGAGCCGGGGCGGCGCGCTGACCGACCGCGAACGC
GAGGTGCTCTCGCACATAGCGGACGGACGTTCGAACCGGGAGATCGCCCGGGCGCTCGTGCTGTCGGAGAAGACGGTGAA
GACGCACGTCTCGAACATCCTGATGAAGCTGGACGTGGCGGACCGCACCCAGGCGGCGCTGTGGGCCGTCCGGCACGGCA
TCGGGGACTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(10-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.928

95.833

0.431
  degU Bacillus subtilis subsp. subtilis str. 168

40.09

100

0.412

Multiple sequence alignment