Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   M444_RS04890 Genome accession   NZ_CP011664
Coordinates   1232999..1233631 (+) Length   210 a.a.
NCBI ID   WP_008742470.1    Uniprot ID   A0ABZ1RUP2
Organism   Streptomyces sp. Mg1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1227999..1238631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M444_RS04870 (M444_04855) - 1228902..1230452 (-) 1551 WP_037796956.1 PH domain-containing protein -
  M444_RS04875 (M444_04860) - 1230449..1230949 (-) 501 WP_008742467.1 PH domain-containing protein -
  M444_RS04880 (M444_04865) - 1231012..1231545 (-) 534 WP_008742468.1 hypothetical protein -
  M444_RS04885 (M444_04870) - 1231711..1233006 (+) 1296 WP_047960437.1 sensor histidine kinase -
  M444_RS04890 (M444_04875) vraR 1232999..1233631 (+) 633 WP_008742470.1 response regulator transcription factor Regulator
  M444_RS04895 (M444_04880) - 1233701..1236574 (-) 2874 WP_235441223.1 AAA family ATPase -
  M444_RS04900 (M444_04885) - 1236790..1237554 (-) 765 WP_008742472.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 22543.02 Da        Isoelectric Point: 5.7971

>NTDB_id=129139 M444_RS04890 WP_008742470.1 1232999..1233631(+) (vraR) [Streptomyces sp. Mg1]
MSEREPIGVLLADDHPVVREGLSAMLELDEGIRVVGQAGSGEEAVLQAGRLRPDIVLLDLRMGAMDGVAATGHILRESPR
SKVVIVTTYEDDADILRAVEAGAAGYLLKGSSREELVNAVKAAARGETVLTPSLAPKLFRARVVEAPVLSERECEVLQLV
RQGLTNADIGRRLFISEATVKTHLLRSFKKLSVSDRTAAVITALERGLLS

Nucleotide


Download         Length: 633 bp        

>NTDB_id=129139 M444_RS04890 WP_008742470.1 1232999..1233631(+) (vraR) [Streptomyces sp. Mg1]
GTGAGTGAGCGCGAACCGATCGGGGTGCTGCTCGCCGATGACCATCCGGTGGTCCGGGAGGGCCTGAGCGCCATGCTGGA
GCTGGACGAGGGCATCCGGGTGGTGGGGCAGGCGGGTTCCGGTGAGGAGGCGGTGCTGCAGGCCGGCCGGCTGCGGCCGG
ACATTGTCCTGCTCGACCTGCGGATGGGCGCGATGGACGGGGTGGCCGCGACCGGGCACATCCTGCGGGAGTCGCCGCGG
AGCAAGGTGGTCATCGTGACCACGTACGAGGACGACGCCGACATCCTGCGCGCGGTGGAGGCGGGCGCGGCGGGCTATCT
GCTGAAGGGCAGTTCACGCGAGGAGCTCGTGAACGCGGTGAAGGCGGCGGCGCGCGGTGAGACGGTGCTGACGCCGTCGC
TGGCGCCGAAGCTGTTCCGGGCCCGGGTGGTGGAGGCGCCGGTGCTGTCGGAGCGGGAGTGCGAGGTGTTGCAGCTGGTC
AGGCAGGGTCTGACCAATGCGGACATCGGGCGCCGGCTGTTCATCAGCGAGGCGACGGTCAAGACGCACCTGTTGCGGTC
GTTCAAGAAGCTGTCGGTGTCGGACCGCACGGCGGCCGTGATCACGGCGCTGGAGCGGGGCCTGCTGTCCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-203)

Response regulator receiver domain (Response_reg)

(9-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.291

98.095

0.395
  degU Bacillus subtilis subsp. subtilis str. 168

34.978

100

0.371