Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   LA24_RS11275 Genome accession   NZ_CP009419
Coordinates   2173478..2173942 (-) Length   154 a.a.
NCBI ID   WP_025463168.1    Uniprot ID   -
Organism   Neisseria meningitidis M7124     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 2171949..2172602 2173478..2173942 flank 876


Gene organization within MGE regions


Location: 2171949..2173942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA24_RS11260 (LA24_11925) - 2171949..2172602 (-) 654 WP_002241060.1 IS1595 family transposase -
  LA24_RS14370 (LA24_11930) - 2172722..2172928 (-) 207 WP_002220254.1 hypothetical protein -
  LA24_RS11270 - 2173160..2173366 (-) 207 WP_025461473.1 hypothetical protein -
  LA24_RS11275 (LA24_11940) comE 2173478..2173942 (-) 465 WP_025463168.1 ComEA family DNA-binding protein Machinery gene

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16561.83 Da        Isoelectric Point: 10.9695

>NTDB_id=129068 LA24_RS11275 WP_025463168.1 2173478..2173942(-) (comE) [Neisseria meningitidis M7124]
MLYPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPVLPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=129068 LA24_RS11275 WP_025463168.1 2173478..2173942(-) (comE) [Neisseria meningitidis M7124]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGCGCGCCCGCACCAAAAGCCCCAGCCAAACCGGTGCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment