Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   LA24_RS10705 Genome accession   NZ_CP009419
Coordinates   2070415..2071059 (-) Length   214 a.a.
NCBI ID   WP_002220358.1    Uniprot ID   A0A0U1RK99
Organism   Neisseria meningitidis M7124     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2065415..2076059
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA24_RS10670 (LA24_11305) ftsL 2065794..2066057 (-) 264 WP_002220363.1 cell division protein FtsL -
  LA24_RS10675 (LA24_11310) rsmH 2066054..2067040 (-) 987 WP_002220362.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
  LA24_RS10680 (LA24_11315) mraZ 2067037..2067492 (-) 456 WP_002218779.1 division/cell wall cluster transcriptional repressor MraZ -
  LA24_RS10685 (LA24_11320) - 2067798..2068988 (+) 1191 WP_050584817.1 class I SAM-dependent methyltransferase -
  LA24_RS10700 (LA24_11335) - 2069561..2070382 (-) 822 WP_002220359.1 undecaprenyl-diphosphate phosphatase -
  LA24_RS10705 (LA24_11340) dsbA1 2070415..2071059 (-) 645 WP_002220358.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  LA24_RS10710 (LA24_11345) ftsN 2071062..2071907 (-) 846 WP_002220356.1 cell division protein FtsN -
  LA24_RS10715 (LA24_11350) comM 2072013..2073509 (-) 1497 WP_002220355.1 YifB family Mg chelatase-like AAA ATPase Machinery gene
  LA24_RS10720 (LA24_11355) - 2073523..2073843 (-) 321 WP_002216505.1 accessory factor UbiK family protein -
  LA24_RS10730 (LA24_11365) putP 2074326..2075852 (+) 1527 WP_002220352.1 sodium/proline symporter PutP -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23970.99 Da        Isoelectric Point: 10.0160

>NTDB_id=129063 LA24_RS10705 WP_002220358.1 2070415..2071059(-) (dsbA1) [Neisseria meningitidis M7124]
MKLKHLLPLLLSAVLSAQAYALTEGEDYLVLDKPIPQKQSGKIEVLEFFGYFCVHCHHFDPLLLKLGKALPSDAYLRTEH
VVWQPEMLGLARMAAAVKLSGLKYQANPAVFKAVYEQKIRLENRSVAEKWALSQKGFDGKKLMRAYDSPAAAAAASKMQQ
LTEQYRIDSTPTVVVGGKYRVIFNNGFDGGVHTIKELVAKVREERKRQTPAVQK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=129063 LA24_RS10705 WP_002220358.1 2070415..2071059(-) (dsbA1) [Neisseria meningitidis M7124]
ATGAAGCTCAAACATCTGTTGCCGCTGCTGCTGTCGGCAGTGTTGTCCGCGCAGGCATATGCCCTGACGGAAGGGGAAGA
CTATCTTGTGTTGGATAAACCCATTCCTCAAAAACAGTCGGGCAAAATTGAGGTTTTGGAATTTTTCGGCTATTTCTGCG
TACATTGCCATCATTTCGATCCTTTGTTATTGAAATTGGGCAAGGCATTGCCGTCTGATGCCTATTTAAGGACGGAGCAC
GTGGTCTGGCAGCCTGAAATGCTCGGTCTGGCAAGAATGGCTGCTGCGGTCAAGCTGTCAGGTTTGAAATATCAGGCAAA
CCCTGCCGTGTTTAAAGCAGTTTACGAACAAAAAATCCGCTTGGAAAACAGGTCGGTTGCCGAAAAATGGGCTTTGTCTC
AAAAAGGCTTTGACGGCAAAAAACTGATGCGCGCCTACGACTCTCCTGCGGCAGCGGCTGCTGCATCAAAAATGCAGCAA
TTGACGGAACAGTACCGCATCGACAGTACGCCGACCGTTGTCGTCGGCGGAAAATACCGCGTTATCTTCAATAATGGCTT
TGACGGCGGTGTTCATACGATTAAAGAATTGGTTGCCAAAGTCAGGGAAGAACGCAAGCGTCAGACCCCTGCTGTACAGA
AATAG

Domains

Predicted by InterproScan.

DSBA-like thioredoxin domain (DSBA)

(86-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1RK99

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

55.851

87.85

0.491
  dsbA2 Neisseria meningitidis MC58

50.538

86.916

0.439

Multiple sequence alignment