Detailed information NTG0128689

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: ABE83_RS20785
• Genome accession: NZ_CP011522
• Coordinates: 4951402..4952526 (-)
• Length: 374 a.a.
• NCBI ID: WP_019764911.1
• Uniprot ID: A0AAD0Q4V1
• Organism: Streptomyces sp. CFMR 7 strain CFMR-7
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4946402..4957526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABE83_RS20760 (ABE83_20805)	cseB	4946675..4947388 (-)	714	WP_018489324.1	two-component system response regulator CseB	-
ABE83_RS20765 (ABE83_20810)	-	4947407..4948057 (-)	651	WP_053560691.1	hypothetical protein	-
ABE83_RS20770 (ABE83_20815)	-	4948231..4949028 (-)	798	WP_053560692.1	SigE family RNA polymerase sigma factor	-
ABE83_RS20775 (ABE83_20820)	-	4949189..4950118 (-)	930	WP_239009196.1	A/G-specific adenine glycosylase	-
ABE83_RS20780 (ABE83_20825)	-	4950370..4951224 (+)	855	WP_203228263.1	hypothetical protein	-
ABE83_RS20785 (ABE83_20830)	disA	4951402..4952526 (-)	1125	WP_019764911.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
ABE83_RS20790 (ABE83_20835)	radA/sms	4952608..4954020 (-)	1413	WP_019764912.1	DNA repair protein RadA	Machinery gene
ABE83_RS36525 (ABE83_20840)	-	4954189..4956228 (+)	2040	WP_239009197.1	hypothetical protein	-
ABE83_RS20800 (ABE83_20845)	-	4956375..4957217 (-)	843	WP_019763451.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40290.25 Da
• Isoelectric Point: 4.9406

>NTDB_id=128689 ABE83_RS20785 WP_019764911.1 4951402..4952526(-) (disA) [Streptomyces sp. CFMR 7 strain CFMR-7]
MAANDRAAAPGKSGQGTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKACGFPVVSVSQSMRLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDALSHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=128689 ABE83_RS20785 WP_019764911.1 4951402..4952526(-) (disA) [Streptomyces sp. CFMR 7 strain CFMR-7]
GTGGCAGCCAACGACCGGGCGGCAGCGCCCGGAAAGTCCGGCCAAGGCACCGGCAACGAAGCGCTGATGCGCGCCTCGTT
GAGCGCGGTCGCGCCCGGAATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGCGGCAACACCGGCGGGCTGATCGTCC
TCGGCATGGACAAGACCGTCGAGTCGATGTGCACCGGCGGGTTCGTGCTGGACGTGGAGTTCACCGCGACCCGGCTGCGG
GAGCTGTGCAAGCTCGACGGGGCGCTGATCCTCGACAAGGACATCACCAAGATCCTGCGGGCCGGGGTGCAGCTGGTCCC
GGACGCCTCGATCCCCACGGAGGAGACGGGCACCCGGCACCGTACGGCGGACCGGGTCTCCAAGGCGTGCGGCTTCCCCG
TCGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGGCGGGTCCTGGAGGAGTCCTCCGCG
ATCCTCTCCCGGGCCAACCAGGCGCTCGCCACGCTGGAGCGGTACAAGCTCCGTCTCGACGAGGTGGCCGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGACGGCGGTGGCGCAGCGGCTGGAGATGGTGCGGCGGATCG
CGACCGAGATCGCGGAGTACGTGGTCGAGCTGGGCACCGACGGCCGGCTCCTCTCGCTCCAGCTCGACGAGCTGATCGCG
GGCGTGGAGCCGGAGCGGGAGCTGGTGGTCCGGGACTACGTGCCCGAGCCGACGGCGAAACGGTCGCGCACGGTGGCGGA
GGCGCTGACGGAGCTGGACGCGCTGAGCCACACGGAGCTGCTGGAGCTGCCGGTGGTGGCACGGGCGCTGGGGTACAGCG
GCTCACCGGAGACGCTGGACTCGGCGGTCTCGCCGCGGGGCTTCCGGCTGCTGGCGAAGGTGCCGAGGCTGCCGGGGGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGGGGCCTCCAGAAGCTGCTGGCGGCCAGCGTGGACGACCTCCAGACCGTGGA
CGGGGTCGGGGAGGCGCGGGCACGCAGCGTGCGGGAAGGGCTCTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: A0AAD0Q4V1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436