Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AW22_RS18610 Genome accession   NZ_CP009300
Coordinates   3331914..3332597 (-) Length   227 a.a.
NCBI ID   WP_000350710.1    Uniprot ID   Q81TR3
Organism   Bacillus cereus D17     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3326914..3337597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AW22_RS18595 (AW22_3477) pepF 3327094..3328920 (-) 1827 WP_000003393.1 oligoendopeptidase F Regulator
  AW22_RS18600 (AW22_3478) - 3328971..3330215 (-) 1245 WP_042513094.1 competence protein CoiA -
  AW22_RS18605 (AW22_3479) - 3330297..3331841 (-) 1545 WP_000799201.1 cardiolipin synthase -
  AW22_RS18610 (AW22_3480) mecA 3331914..3332597 (-) 684 WP_000350710.1 adaptor protein MecA Regulator
  AW22_RS18615 (AW22_3481) - 3332924..3333598 (+) 675 WP_000362618.1 TerC family protein -
  AW22_RS18620 (AW22_3482) spx 3333648..3334043 (-) 396 WP_000258267.1 transcriptional regulator Spx -
  AW22_RS18630 (AW22_3483) - 3334637..3334840 (+) 204 WP_000559980.1 hypothetical protein -
  AW22_RS18635 (AW22_3484) - 3334869..3336515 (-) 1647 WP_000728613.1 peptide ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26966.00 Da        Isoelectric Point: 3.9822

>NTDB_id=128365 AW22_RS18610 WP_000350710.1 3331914..3332597(-) (mecA) [Bacillus cereus D17]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=128365 AW22_RS18610 WP_000350710.1 3331914..3332597(-) (mecA) [Bacillus cereus D17]
TTGGATATTGAAAGAATTAATGATCATACGATGAAGTTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAAATTTGGTATGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGCATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAAGAACAAGCAGGAACAAACTTTAACGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAGGAAGAAATTGATCGCATTTTAAG
TATTGTTTTAGAATACGGAGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81TR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

56.14

100

0.564

Multiple sequence alignment