Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AA105_RS02280 Genome accession   NZ_CP011419
Coordinates   432751..433392 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain NSUI002     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 427751..438392
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA105_RS02260 (AA105_02265) - 427919..428656 (+) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  AA105_RS02265 (AA105_02270) stkP 428656..430650 (+) 1995 WP_009909429.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  AA105_RS02270 (AA105_02275) liaF 431071..431766 (+) 696 WP_009909430.1 cell wall-active antibiotics response protein LiaF -
  AA105_RS02275 (AA105_02280) - 431763..432779 (+) 1017 WP_002937028.1 sensor histidine kinase -
  AA105_RS02280 (AA105_02285) vraR 432751..433392 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  AA105_RS02285 (AA105_02290) - 433442..434842 (+) 1401 WP_002937018.1 Cof-type HAD-IIB family hydrolase -
  AA105_RS02290 (AA105_02295) - 434844..435215 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  AA105_RS02295 (AA105_02300) cysK 435242..436168 (-) 927 WP_002937015.1 cysteine synthase A -
  AA105_RS02300 (AA105_02305) - 436398..437555 (-) 1158 WP_024409220.1 site-specific integrase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=128183 AA105_RS02280 WP_002937025.1 432751..433392(+) (vraR) [Streptococcus suis strain NSUI002]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=128183 AA105_RS02280 WP_002937025.1 432751..433392(+) (vraR) [Streptococcus suis strain NSUI002]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCTAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCCGCTATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCTTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413

Multiple sequence alignment