Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   NCDO2118_RS08440 Genome accession   NZ_CP009054
Coordinates   1766852..1768327 (-) Length   491 a.a.
NCBI ID   WP_012898208.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis NCDO 2118     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1761852..1773327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NCDO2118_RS08420 (NCDO2118_1632) murG 1761989..1763062 (-) 1074 WP_003130746.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  NCDO2118_RS08425 (NCDO2118_1633) murD 1763272..1764624 (-) 1353 WP_003130748.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  NCDO2118_RS08430 (NCDO2118_1634) - 1764955..1765296 (-) 342 WP_012898206.1 P-II family nitrogen regulator -
  NCDO2118_RS08435 (NCDO2118_1635) - 1765428..1766669 (-) 1242 WP_012898207.1 ammonium transporter -
  NCDO2118_RS08440 (NCDO2118_1636) covS 1766852..1768327 (-) 1476 WP_012898208.1 HAMP domain-containing histidine kinase Regulator
  NCDO2118_RS08445 (NCDO2118_1637) covR 1768336..1769028 (-) 693 WP_012898209.1 response regulator transcription factor Regulator
  NCDO2118_RS08450 (NCDO2118_1638) - 1769184..1769714 (-) 531 WP_012898210.1 YceD family protein -
  NCDO2118_RS08455 (NCDO2118_1639) - 1769845..1770090 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  NCDO2118_RS13770 - 1770246..1770443 (-) 198 WP_235187788.1 hypothetical protein -
  NCDO2118_RS13775 - 1770449..1770712 (-) 264 WP_235187789.1 hypothetical protein -
  NCDO2118_RS08465 (NCDO2118_1641) - 1770794..1771156 (-) 363 WP_012898212.1 TIGR02328 family protein -
  NCDO2118_RS13580 - 1771373..1771519 (-) 147 WP_235187790.1 hypothetical protein -
  NCDO2118_RS08470 (NCDO2118_1642) - 1771616..1772161 (-) 546 WP_235187791.1 metallophosphoesterase -
  NCDO2118_RS12970 (NCDO2118_1643) - 1772446..1772697 (-) 252 WP_144242123.1 hypothetical protein -
  NCDO2118_RS12975 - 1772801..1772986 (-) 186 WP_235187792.1 DUF1211 domain-containing protein -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56205.12 Da        Isoelectric Point: 4.8253

>NTDB_id=126431 NCDO2118_RS08440 WP_012898208.1 1766852..1768327(-) (covS) [Lactococcus lactis subsp. lactis NCDO 2118]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=126431 NCDO2118_RS08440 WP_012898208.1 1766852..1768327(-) (covS) [Lactococcus lactis subsp. lactis NCDO 2118]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATAAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCACGTTTACAATGATATGATGTTGAAGATGAAGGCGTATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCACGAGTTAAGAACACCCTTAGCTGTCTTGGATGGACATATTAACTTGCTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGGCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTACATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTGATTACGAGTGTGTCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAACGTTTCTTTAGAGCGGATAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTACCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

ArlS sensor domain (ArlS_N)

(54-185)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

99.796

100

0.998

Multiple sequence alignment