Detailed information NTG0125815

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DP15_RS08530
• Genome accession: NZ_CP008926
• Coordinates: 1694996..1696225 (+)
• Length: 409 a.a.
• NCBI ID: WP_009880296.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain ATCC 19615
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1689996..1701225

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DP15_RS08510 (DP15_1735)	-	1690612..1691889 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
DP15_RS08515 (DP15_1736)	-	1691876..1693051 (-)	1176	WP_038432910.1	hydroxymethylglutaryl-CoA synthase	-
DP15_RS08520 (DP15_1737)	-	1693260..1694099 (+)	840	WP_011017679.1	thymidylate synthase	-
DP15_RS08525 (DP15_1738)	-	1694179..1694676 (+)	498	WP_002984955.1	dihydrofolate reductase	-
DP15_RS10030 (DP15_1739)	-	1694696..1694866 (+)	171	WP_002990165.1	hypothetical protein	-
DP15_RS08530 (DP15_1740)	clpX	1694996..1696225 (+)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DP15_RS08535 (DP15_1741)	yihA	1696235..1696834 (+)	600	WP_038432912.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DP15_RS08540 (DP15_1742)	-	1696982..1697725 (+)	744	WP_002984942.1	hypothetical protein	-
DP15_RS08545 (DP15_1743)	-	1697783..1699882 (-)	2100	WP_038432914.1	AAA family ATPase	-
DP15_RS08550 (DP15_1744)	rpiA	1700260..1700943 (+)	684	WP_002994002.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45020.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=125815 DP15_RS08530 WP_009880296.1 1694996..1696225(+) (clpX) [Streptococcus pyogenes strain ATCC 19615]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=125815 DP15_RS08530 WP_009880296.1 1694996..1696225(+) (clpX) [Streptococcus pyogenes strain ATCC 19615]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTAGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575