Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ID09_RS08740 Genome accession   NZ_CP008921
Coordinates   1781903..1782592 (-) Length   229 a.a.
NCBI ID   WP_024381695.1    Uniprot ID   -
Organism   Streptococcus suis 6407     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1776903..1787592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS08715 (ID09_08960) - 1777675..1778826 (-) 1152 WP_024381692.1 replication initiation/membrane attachment protein -
  ID09_RS08720 (ID09_08965) nrdR 1778813..1779304 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  ID09_RS08725 (ID09_08970) - 1779376..1780506 (-) 1131 WP_024381693.1 AI-2E family transporter -
  ID09_RS08730 (ID09_08975) - 1780735..1781259 (-) 525 WP_015647271.1 hypothetical protein -
  ID09_RS08740 (ID09_08985) covR 1781903..1782592 (-) 690 WP_024381695.1 DNA-binding response regulator Regulator
  ID09_RS08745 (ID09_08990) gndA 1782674..1784101 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  ID09_RS08750 (ID09_08995) - 1784198..1784737 (-) 540 WP_024381696.1 YceD family protein -
  ID09_RS08755 (ID09_09000) trxB 1784747..1785664 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  ID09_RS08760 (ID09_09005) - 1785678..1785902 (-) 225 WP_002936682.1 DUF4059 family protein -
  ID09_RS08765 (ID09_09010) - 1785920..1787263 (-) 1344 WP_024380515.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26239.14 Da        Isoelectric Point: 5.4013

>NTDB_id=125710 ID09_RS08740 WP_024381695.1 1781903..1782592(-) (covR) [Streptococcus suis 6407]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISELVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=125710 ID09_RS08740 WP_024381695.1 1781903..1782592(-) (covR) [Streptococcus suis 6407]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTGGTGAAGCCCTTTGTCAT
CAGTGAGTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.052

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.373

100

0.437

Multiple sequence alignment