Detailed information NTG0124987

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: HW03_RS05720
• Genome accession: NZ_CP008863
• Coordinates: 1237400..1239625 (-)
• Length: 741 a.a.
• NCBI ID: WP_003119806.1
• Uniprot ID: A0A1S1C5Z8
• Organism: Pseudomonas aeruginosa strain M37351
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1232400..1244625

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HW03_RS05685 (HW03_05745)	murB	1232790..1233809 (-)	1020	WP_003091153.1	UDP-N-acetylmuramate dehydrogenase	-
HW03_RS05690 (HW03_05750)	-	1233806..1234270 (-)	465	WP_003091154.1	low molecular weight protein-tyrosine-phosphatase	-
HW03_RS05695 (HW03_05755)	kdsB	1234270..1235034 (-)	765	WP_003091155.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
HW03_RS05700 (HW03_05760)	-	1235034..1235219 (-)	186	WP_003091157.1	Trm112 family protein	-
HW03_RS05705 (HW03_05765)	lpxK	1235257..1236255 (-)	999	WP_003091159.1	tetraacyldisaccharide 4'-kinase	-
HW03_RS05710 (HW03_05770)	-	1236255..1236695 (-)	441	WP_003091161.1	ExbD/TolR family protein	-
HW03_RS05715 (HW03_05775)	exbB	1236692..1237327 (-)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
HW03_RS05720 (HW03_05780)	comA	1237400..1239625 (-)	2226	WP_003119806.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HW03_RS05725 (HW03_05785)	-	1239756..1240289 (+)	534	WP_003091165.1	DUF2062 domain-containing protein	-
HW03_RS05730 (HW03_05790)	-	1240377..1241621 (-)	1245	WP_003113987.1	lipoprotein-releasing ABC transporter permease subunit	-
HW03_RS05735 (HW03_05795)	lolD	1241691..1242374 (-)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
HW03_RS05740 (HW03_05800)	-	1242367..1243617 (-)	1251	WP_003091170.1	lipoprotein-releasing ABC transporter permease subunit	-
HW03_RS05745 (HW03_05805)	-	1243720..1244319 (+)	600	WP_003105196.1	PilZ domain-containing protein	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 80048.70 Da
• Isoelectric Point: 10.5155

>NTDB_id=124987 HW03_RS05720 WP_003119806.1 1237400..1239625(-) (comA) [Pseudomonas aeruginosa strain M37351]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVRAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHVLLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPVWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=124987 HW03_RS05720 WP_003119806.1 1237400..1239625(-) (comA) [Pseudomonas aeruginosa strain M37351]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCCGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCACGGTGAAGGCGGGCCAGCGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGGTTGAGCGCGGCCGAGT
GGCGCATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCGGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGCGCCTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTGTGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCATTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGAGAGCATGTCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGTTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCACAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A1S1C5Z8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.807	97.301	0.572
comA	Ralstonia pseudosolanacearum GMI1000	35.48	100	0.364