Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   TK78_RS28485 Genome accession   NZ_CP010833
Coordinates   6425617..6426261 (+) Length   214 a.a.
NCBI ID   WP_006123560.1    Uniprot ID   A0A5D4HJE9
Organism   Streptomyces sp. Tue 6075 strain Tue6075     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6420617..6431261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TK78_RS28465 (TK78_27955) - 6421220..6421996 (-) 777 WP_032778448.1 transglycosylase SLT domain-containing protein -
  TK78_RS28470 (TK78_27960) - 6422269..6423513 (-) 1245 WP_079181549.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  TK78_RS28475 (TK78_27965) - 6423510..6424235 (-) 726 WP_075267068.1 SDR family oxidoreductase -
  TK78_RS28480 (TK78_27970) - 6424479..6425624 (+) 1146 WP_075267069.1 GAF domain-containing sensor histidine kinase -
  TK78_RS28485 (TK78_27975) vraR 6425617..6426261 (+) 645 WP_006123560.1 response regulator transcription factor Regulator
  TK78_RS28490 (TK78_27980) - 6426409..6426660 (+) 252 WP_030586340.1 chaplin family protein -
  TK78_RS28495 (TK78_27985) - 6427176..6427967 (-) 792 WP_075267070.1 hypothetical protein -
  TK78_RS28500 (TK78_27990) - 6428112..6428909 (+) 798 WP_075267071.1 ABC transporter ATP-binding protein -
  TK78_RS28505 (TK78_27995) - 6429016..6429444 (+) 429 WP_006123556.1 NfeD family protein -
  TK78_RS28510 (TK78_28000) - 6429609..6430589 (+) 981 WP_032761334.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23141.45 Da        Isoelectric Point: 5.3843

>NTDB_id=124765 TK78_RS28485 WP_006123560.1 6425617..6426261(+) (vraR) [Streptomyces sp. Tue 6075 strain Tue6075]
MADKIIRVLLVDDHQVVRRGLRTFLEIQEDIEVVGEASDGAEGVARTEELRPDVVLMDIKMPGTDGIEALRRLRELDNPA
KVLIVTSFTEQRTVVPALRAGASGYVYKDVDPDALAGAIRSVHAGHVLLQPEVAGALLAQEDTGTGTGRGSTLTEREREV
LGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGAVG

Nucleotide


Download         Length: 645 bp        

>NTDB_id=124765 TK78_RS28485 WP_006123560.1 6425617..6426261(+) (vraR) [Streptomyces sp. Tue 6075 strain Tue6075]
GTGGCTGACAAGATCATCAGGGTGCTGCTGGTCGACGACCATCAGGTGGTCCGCCGCGGACTGCGCACGTTCCTGGAGAT
CCAGGAGGACATAGAGGTCGTCGGCGAGGCGTCCGACGGCGCGGAGGGCGTGGCCCGGACCGAGGAGCTGCGCCCCGACG
TCGTGCTGATGGACATCAAGATGCCCGGCACCGACGGCATCGAGGCGCTGCGCCGCCTGCGCGAGCTGGACAACCCGGCC
AAGGTCCTCATCGTCACCAGCTTCACCGAACAGCGCACCGTGGTCCCCGCCCTGCGCGCCGGAGCCTCCGGTTACGTCTA
CAAGGACGTCGACCCGGACGCCCTGGCGGGGGCGATCCGCTCCGTCCACGCCGGACACGTCCTGCTCCAGCCCGAGGTCG
CCGGCGCCCTCCTCGCCCAGGAGGACACGGGCACCGGCACGGGCCGGGGGAGCACCCTCACCGAACGGGAACGCGAGGTC
CTCGGCCTCATCGCGGACGGCCGTTCGAACCGGGAGATCGCCCGGGCCCTCGTCCTCTCCGAGAAGACGGTCAAGACCCA
CGTCTCGAACATCCTCATGAAACTCGACCTGGCCGACCGTACCCAGGCGGCGCTGTGGGCGGTACGCCACGGAGCGGTGG
GCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-119)

Bacterial regulatory proteins, luxR family (GerE)

(152-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5D4HJE9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

97.664

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

39.462

100

0.411

Multiple sequence alignment