Detailed information NTG0124764

Bioinformatically predicted

Overview

• Name: vraR
• Type: Regulator
• Locus tag: TK78_RS28110
• Genome accession: NZ_CP010833
• Coordinates: 6347698..6348360 (-)
• Length: 220 a.a.
• NCBI ID: WP_075267014.1
• Uniprot ID: -
• Organism: Streptomyces sp. Tue 6075 strain Tue6075
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 6342698..6353360

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TK78_RS28095 (TK78_27590)	-	6343752..6345017 (-)	1266	WP_075267011.1	MFS transporter	-
TK78_RS28100 (TK78_27595)	-	6345119..6346045 (-)	927	WP_075267012.1	alpha/beta fold hydrolase	-
TK78_RS28105 (TK78_27600)	-	6346152..6347603 (-)	1452	WP_075267013.1	penicillin-binding transpeptidase domain-containing protein	-
TK78_RS28110 (TK78_27605)	vraR	6347698..6348360 (-)	663	WP_075267014.1	response regulator transcription factor	Regulator
TK78_RS28115 (TK78_27610)	-	6348357..6349658 (-)	1302	WP_075267015.1	histidine kinase	-
TK78_RS28120 (TK78_27615)	-	6349655..6350737 (-)	1083	WP_203233263.1	hypothetical protein	-
TK78_RS28125 (TK78_27620)	-	6350840..6351319 (-)	480	WP_075267016.1	GNAT family N-acetyltransferase	-
TK78_RS28130 (TK78_27625)	-	6351319..6352089 (-)	771	WP_006123634.1	IclR family transcriptional regulator	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 23262.66 Da
• Isoelectric Point: 4.8331

>NTDB_id=124764 TK78_RS28110 WP_075267014.1 6347698..6348360(-) (vraR) [Streptomyces sp. Tue 6075 strain Tue6075]
MSGAPVRVVLADDERMVRTALRVILDAEEGIEVVGEATTGAEAVSVVRELRPDVVLMDVRMPETDGIRATEQILSTLEDP
PRIVVVTTFENDAYVYDALHAGAAGFLLKRAAAEELVQAVRLVACGDSLLYPAAVRTLAAEHAARQPARAPAWVARLTDR
EADVLRLMAAGLTNAEIAGRLSVGPATAKTHVAAVLAKTGARDRTQAVIAAYESGFITPG

Nucleotide

• Length: 663 bp

>NTDB_id=124764 TK78_RS28110 WP_075267014.1 6347698..6348360(-) (vraR) [Streptomyces sp. Tue 6075 strain Tue6075]
ATGAGCGGGGCTCCGGTGCGGGTGGTGCTCGCGGACGACGAGCGGATGGTGCGCACGGCACTGCGGGTGATTCTGGACGC
CGAGGAGGGCATCGAGGTCGTCGGGGAGGCGACCACCGGCGCGGAGGCCGTCTCCGTGGTGCGGGAGCTGCGGCCCGACG
TGGTGCTGATGGACGTACGGATGCCGGAGACCGACGGCATCCGGGCCACGGAGCAGATCCTCTCCACCCTGGAGGACCCG
CCGAGGATCGTCGTCGTGACGACCTTCGAGAACGACGCGTACGTGTACGACGCCCTGCACGCCGGGGCGGCCGGGTTCCT
GCTGAAGCGGGCGGCGGCGGAGGAGCTGGTGCAGGCGGTGCGTCTGGTGGCGTGCGGCGACTCGCTCCTCTACCCGGCGG
CGGTGCGCACGCTGGCCGCCGAGCACGCGGCGCGCCAACCGGCCAGAGCCCCGGCGTGGGTGGCGCGGCTGACGGACCGG
GAGGCGGACGTGCTGCGGCTGATGGCGGCGGGGCTGACCAACGCGGAGATCGCGGGCCGGCTGTCGGTGGGCCCGGCGAC
GGCGAAGACGCATGTGGCCGCTGTCCTCGCGAAGACCGGCGCCCGGGACCGCACCCAGGCGGTGATCGCGGCGTACGAGT
CCGGTTTCATCACCCCGGGCTGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (8-121)

• Bacterial regulatory proteins, luxR family (GerE) (157-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraR	Staphylococcus aureus N315	38.318	97.273	0.373
degU	Bacillus subtilis subsp. subtilis str. 168	35.398	100	0.364