Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   TK78_RS25560 Genome accession   NZ_CP010833
Coordinates   5789028..5789717 (-) Length   229 a.a.
NCBI ID   WP_075266635.1    Uniprot ID   -
Organism   Streptomyces sp. Tue 6075 strain Tue6075     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5784028..5794717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TK78_RS25550 (TK78_25065) - 5786513..5787745 (-) 1233 WP_075266633.1 acyltransferase -
  TK78_RS25555 (TK78_25070) - 5787742..5788857 (-) 1116 WP_075266634.1 alpha/beta hydrolase -
  TK78_RS25560 (TK78_25075) vraR 5789028..5789717 (-) 690 WP_075266635.1 response regulator transcription factor Regulator
  TK78_RS25565 (TK78_25080) - 5789714..5791090 (-) 1377 WP_075266636.1 sensor histidine kinase -
  TK78_RS25570 (TK78_25085) - 5791287..5792255 (-) 969 WP_075266637.1 DUF4429 domain-containing protein -
  TK78_RS25575 (TK78_25090) - 5792342..5793550 (-) 1209 WP_075266638.1 alpha/beta hydrolase -
  TK78_RS25580 (TK78_25095) - 5793714..5794367 (-) 654 WP_075266639.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 24273.94 Da        Isoelectric Point: 5.0891

>NTDB_id=124760 TK78_RS25560 WP_075266635.1 5789028..5789717(-) (vraR) [Streptomyces sp. Tue 6075 strain Tue6075]
MTIRVIIVDDQAMVRAGFAALLAAQSDIDVVGEAADGRQGVDVSRNQHPDVVLMDVRMPEMDGLAAARELLNPPPGVVHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVAAGDALLAPSVTRRLIADFAAQRPAGATRTGQALRLN
GLTPRESEVLELIARGLSNQEIAGRLVLAEQTVKTHIGRVLAKLDLRDRAQAVIFAYESGLVTPGDAGA

Nucleotide


Download         Length: 690 bp        

>NTDB_id=124760 TK78_RS25560 WP_075266635.1 5789028..5789717(-) (vraR) [Streptomyces sp. Tue 6075 strain Tue6075]
GTGACCATCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCCGGGTTCGCGGCGCTGCTGGCGGCGCAGAGCGA
CATCGACGTGGTGGGCGAGGCGGCGGACGGCCGCCAGGGCGTGGACGTCAGCCGCAACCAGCATCCCGACGTGGTCCTGA
TGGACGTGCGGATGCCGGAGATGGACGGACTGGCCGCCGCGCGCGAGCTGTTGAACCCGCCGCCGGGGGTGGTGCACCGG
CCGAAGGTCCTGATGCTGACGACGTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCCGGGGCGTCCGGTTTCCT
GCTGAAGGACGCGCCGCCCGCCGATCTGATCGCGGCGGTACGGGTGGTGGCGGCCGGGGACGCGCTGCTCGCGCCCTCGG
TGACCCGGCGGCTGATCGCGGACTTCGCGGCGCAGCGGCCCGCCGGGGCGACGCGCACCGGGCAGGCGCTCCGGCTCAAC
GGGCTGACACCGCGCGAGAGCGAGGTGCTGGAGCTGATCGCCCGGGGTCTTTCGAACCAGGAGATCGCGGGTCGTCTGGT
GCTGGCCGAGCAGACCGTCAAGACGCACATCGGGCGGGTGCTGGCCAAGCTGGACCTGCGGGACCGGGCGCAGGCGGTCA
TCTTCGCGTACGAGTCGGGTCTGGTGACGCCGGGGGACGCGGGGGCGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(162-216)

Response regulator receiver domain (Response_reg)

(5-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.991

96.943

0.397
  degU Bacillus subtilis subsp. subtilis str. 168

37.004

99.127

0.367