Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   TK78_RS15945 Genome accession   NZ_CP010833
Coordinates   3661659..3662327 (-) Length   222 a.a.
NCBI ID   WP_006126329.1    Uniprot ID   A0A2U8NNZ9
Organism   Streptomyces sp. Tue 6075 strain Tue6075     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3656659..3667327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TK78_RS15920 (TK78_15620) - 3657219..3658502 (-) 1284 WP_026237801.1 adenylosuccinate synthase -
  TK78_RS15925 (TK78_15625) - 3658689..3659576 (+) 888 WP_075265119.1 diacylglycerol kinase -
  TK78_RS15930 (TK78_15630) - 3659631..3659903 (+) 273 WP_010063219.1 DUF1876 domain-containing protein -
  TK78_RS15935 (TK78_15635) - 3660036..3660377 (+) 342 WP_075265120.1 hypothetical protein -
  TK78_RS15940 (TK78_15640) - 3660388..3661593 (-) 1206 WP_075265121.1 cytochrome P450 -
  TK78_RS15945 (TK78_15645) vraR 3661659..3662327 (-) 669 WP_006126329.1 response regulator transcription factor Regulator
  TK78_RS15950 (TK78_15650) - 3662324..3663661 (-) 1338 WP_075265122.1 histidine kinase -
  TK78_RS15955 (TK78_15655) - 3663798..3664619 (-) 822 WP_075268407.1 NAD(P)H-binding protein -
  TK78_RS15960 (TK78_15660) - 3664751..3665668 (-) 918 WP_075265123.1 alpha/beta hydrolase -
  TK78_RS15965 (TK78_15665) kynU 3665857..3667083 (-) 1227 WP_075265124.1 kynureninase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24047.84 Da        Isoelectric Point: 4.7242

>NTDB_id=124734 TK78_RS15945 WP_006126329.1 3661659..3662327(-) (vraR) [Streptomyces sp. Tue 6075 strain Tue6075]
MSDTDIRVLIVDDQMMVREGFSVLLNAMPGITVVGEALDGRQALDQVAALRPDVVLMDIRMPEMNGIEATREIVARDADA
KVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTRRLITEFSKLAETPRPPALARIGDLT
ERETEVLVLIAQGLSNAEIASHLIVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=124734 TK78_RS15945 WP_006126329.1 3661659..3662327(-) (vraR) [Streptomyces sp. Tue 6075 strain Tue6075]
ATGAGCGACACCGACATCCGGGTCCTGATCGTCGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTCCTGCTCAACGC
GATGCCCGGGATCACCGTCGTGGGCGAGGCGCTGGACGGCCGGCAGGCGCTCGACCAGGTCGCCGCCCTGCGCCCGGACG
TCGTCCTGATGGACATCCGCATGCCCGAGATGAACGGCATCGAGGCGACCCGCGAGATCGTCGCCCGGGACGCCGACGCG
AAGGTCCTGGTGCTGACGACCTTCGACCTCGACGAGTACGTCTACCAGGCGCTGCGGGCCGGGGCGTCGGGCTTCCTCCT
CAAGGACGCCTCGGCCCGTCAGCTCGCCGACGGGGTACGGGTGGTGGCGTCGGGCGAGGCGCTGCTCGCCCCGACGGTCA
CCCGGCGGCTGATCACCGAGTTCTCCAAGCTCGCGGAGACCCCGCGCCCGCCCGCCCTGGCCCGGATCGGGGATCTCACC
GAGCGCGAGACGGAGGTGCTCGTGCTCATCGCGCAGGGGCTCTCCAACGCGGAGATCGCCTCGCACCTGATCGTCGCCGA
GTCCACGATCAAGACGCACGTCAGCCGCATCCTGGTGAAGCTGGGGCTGCGCGACCGGACGCAGGCGGCGGTGTTCGCGT
ACGAGGCGCGGCTGGTCACGCCGGGGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(159-213)

Response regulator receiver domain (Response_reg)

(8-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2U8NNZ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.925

96.396

0.423
  degU Bacillus subtilis subsp. subtilis str. 168

42.466

98.649

0.419