Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   SP5448_RS09970 Genome accession   NZ_CP008776
Coordinates   48318..48413 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 5448     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 43318..53413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP5448_RS00250 (SP5448_00260) - 44238..45881 (+) 1644 WP_010921779.1 AIPR family protein -
  SP5448_RS00255 (SP5448_00265) purB 45899..47191 (+) 1293 WP_010921780.1 adenylosuccinate lyase -
  SP5448_RS00260 (SP5448_00270) comR 47323..48234 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  SP5448_RS09970 comS 48318..48413 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  SP5448_RS00265 (SP5448_00280) ruvB 48460..49458 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  SP5448_RS00270 (SP5448_00285) - 49596..50033 (+) 438 WP_002994668.1 low molecular weight phosphotyrosine protein phosphatase -
  SP5448_RS00275 (SP5448_00290) - 50056..50457 (+) 402 WP_010921781.1 MORN repeat-containing protein -
  SP5448_RS00280 (SP5448_00295) - 50454..52229 (+) 1776 WP_010921782.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=124166 SP5448_RS09970 WP_198462994.1 48318..48413(+) (comS) [Streptococcus pyogenes strain 5448]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=124166 SP5448_RS09970 WP_198462994.1 48318..48413(+) (comS) [Streptococcus pyogenes strain 5448]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1
  comS Streptococcus pyogenes MGAS315

45.161

100

0.452

Multiple sequence alignment