Detailed information NTG0124023

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SHYC_RS04300
• Genome accession: NZ_CP008747
• Coordinates: 935862..936905 (+)
• Length: 347 a.a.
• NCBI ID: WP_039644794.1
• Uniprot ID: -
• Organism: Staphylococcus hyicus strain ATCC 11249
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 930862..941905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SHYC_RS04275 (SHYC_04370)	-	931740..932471 (+)	732	WP_039644786.1	type 1 glutamine amidotransferase	-
SHYC_RS04280 (SHYC_04375)	-	932583..933608 (-)	1026	WP_039644788.1	aromatic acid exporter family protein	-
SHYC_RS04285 (SHYC_04380)	map	933902..934660 (+)	759	WP_039644790.1	type I methionyl aminopeptidase	-
SHYC_RS04290 (SHYC_04385)	-	934759..935145 (+)	387	WP_052257806.1	hypothetical protein	-
SHYC_RS04295 (SHYC_04390)	liaF	935158..935865 (+)	708	WP_039644793.1	cell wall-active antibiotics response protein LiaF	-
SHYC_RS04300 (SHYC_04395)	vraS	935862..936905 (+)	1044	WP_039644794.1	sensor histidine kinase	Regulator
SHYC_RS04305 (SHYC_04400)	vraR	936895..937524 (+)	630	WP_039644795.1	response regulator transcription factor	Regulator
SHYC_RS04310 (SHYC_04405)	-	937588..938157 (-)	570	WP_039644796.1	carbonic anhydrase	-
SHYC_RS04315 (SHYC_04410)	-	938192..939463 (-)	1272	WP_039644798.1	YihY/virulence factor BrkB family protein	-
SHYC_RS04320 (SHYC_04415)	-	939583..939858 (-)	276	WP_039644801.1	hypothetical protein	-
SHYC_RS04325 (SHYC_04420)	-	939865..940323 (-)	459	WP_039644802.1	low molecular weight protein-tyrosine-phosphatase	-
SHYC_RS04330 (SHYC_04425)	-	940456..940665 (+)	210	WP_039644804.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39865.89 Da
• Isoelectric Point: 4.8594

>NTDB_id=124023 SHYC_RS04300 WP_039644794.1 935862..936905(+) (vraS) [Staphylococcus hyicus strain ATCC 11249]
MNQYVRSIGSMLILVYSLFTAFFFIDNVFTNIIFFQGMFYTQIFGIPVFLFLNLITIFLCIIVGSVLAYKNNQQSDWLKA
QIERAIEGETVGVNDQQIEIYLETLELYEALVPLNQELHRMRIKTQNLTNESYNMNDSKVQKIIEDERHRLARELHDSVS
QQLFAASMMLSAIKETPLDPPLNQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIQTLVSDLQRKVPLKVVQDI
GEFDVPKGMEDHLFRITQEAISNTLRHSKGTEVTVELLQREDYILLRIQDDGIGFNVDEKMEQSYGLKNMRERAMEIGAT
FHIVSLPDSGTRIEVKAPLDKEGHNDN

Nucleotide

• Length: 1044 bp

>NTDB_id=124023 SHYC_RS04300 WP_039644794.1 935862..936905(+) (vraS) [Staphylococcus hyicus strain ATCC 11249]
ATGAATCAATATGTACGATCGATAGGTTCAATGCTAATACTTGTGTATAGTTTATTTACAGCTTTCTTTTTTATCGACAA
TGTTTTCACAAATATCATTTTTTTCCAAGGCATGTTTTATACGCAAATATTTGGGATTCCAGTATTTTTGTTTTTAAATC
TTATTACTATATTTTTATGTATTATCGTAGGAAGTGTGCTTGCATATAAAAACAATCAACAAAGCGATTGGTTGAAGGCG
CAAATTGAGCGTGCCATTGAAGGTGAAACGGTAGGTGTCAATGATCAACAAATCGAAATTTATCTAGAAACGTTAGAACT
TTATGAAGCATTAGTGCCACTTAATCAAGAATTACATCGCATGCGCATTAAAACACAAAATTTAACGAATGAGTCTTACA
ATATGAATGACTCAAAAGTACAAAAAATTATTGAGGATGAACGACATCGCCTTGCTAGAGAATTACATGATAGCGTGTCA
CAACAATTATTTGCGGCAAGCATGATGCTTTCAGCAATTAAAGAAACACCTTTAGATCCACCTTTGAACCAGCAAATACC
GACACTTGAAAAAATGGTCCAGGATTCACAACTTGAAATGCGCGCACTCTTGTTACATTTACGACCTATAGGATTGAAGG
ACAAGTCATTAGGAGAAGGCATTCAAACTTTAGTTAGTGATCTTCAGCGTAAGGTACCTTTAAAAGTCGTGCAAGATATT
GGTGAGTTTGATGTTCCAAAAGGTATGGAAGATCATTTGTTTAGAATTACCCAAGAAGCCATTTCTAATACATTACGTCA
TTCTAAAGGGACTGAAGTGACCGTAGAATTATTACAACGTGAAGATTACATACTGTTACGTATTCAAGATGATGGTATTG
GCTTTAATGTTGATGAAAAAATGGAACAAAGCTATGGCTTGAAAAATATGCGTGAGCGCGCAATGGAAATAGGCGCTACA
TTTCATATCGTATCTTTACCTGACTCAGGAACGAGAATTGAAGTGAAAGCACCATTAGACAAGGAGGGGCACAATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (250-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	81.556	100	0.816