Detailed information NTG0122986

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BMMGA3_RS04375
• Genome accession: NZ_CP007739
• Coordinates: 877959..880598 (+)
• Length: 879 a.a.
• NCBI ID: WP_004433581.1
• Uniprot ID: I3E7N7
• Organism: Bacillus methanolicus MGA3
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 872959..885598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BMMGA3_RS04360 (BMMGA3_04445)	-	873488..876601 (+)	3114	WP_004433574.1	carbamoyl phosphate synthase large subunit	-
BMMGA3_RS04365 (BMMGA3_04450)	argF	876598..877551 (+)	954	WP_004433577.1	ornithine carbamoyltransferase	-
BMMGA3_RS04370 (BMMGA3_04455)	-	877677..877856 (+)	180	WP_004433579.1	YjzC family protein	-
BMMGA3_RS04375 (BMMGA3_04460)	clpC	877959..880598 (+)	2640	WP_004433581.1	ATP-dependent chaperone ClpB	Regulator
BMMGA3_RS04380 (BMMGA3_04465)	-	880732..880914 (-)	183	WP_004433583.1	YjzD family protein	-
BMMGA3_RS04385 (BMMGA3_04470)	-	881117..881854 (+)	738	WP_004433585.1	hypothetical protein	-
BMMGA3_RS04390 (BMMGA3_04475)	-	881935..882798 (+)	864	WP_004433587.1	hypothetical protein	-
BMMGA3_RS04395 (BMMGA3_04480)	med	882966..883916 (+)	951	WP_004433592.1	BMP family ABC transporter substrate-binding protein	Regulator
BMMGA3_RS04400 (BMMGA3_04485)	-	883975..884277 (-)	303	WP_004433594.1	hypothetical protein	-
BMMGA3_RS04405 (BMMGA3_04490)	-	884494..885426 (+)	933	WP_004433595.1	beta-ketoacyl-ACP synthase III	-

Sequence

Protein

• Length: 879 a.a.
• Molecular weight: 99560.97 Da
• Isoelectric Point: 5.2139

>NTDB_id=122986 BMMGA3_RS04375 WP_004433581.1 877959..880598(+) (clpC) [Bacillus methanolicus MGA3]
MDINRMTERLQQAFLRAQTLATQNQHQEIDDVHIFLALLEDENSLVHSILEKLQLSSNDFKNKLENLLAKKPQVIGSGVE
QGKVYITPVLQKVLAEAETQMKLFNDEYLSVEHILLAAINTEQSAAGQVLKNFRVTIQSALEAIKEIRGNQRVTTQNPES
TYEALKKYGRDLVAEVKEGKIDPVIGRDSEIRNVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPEGLKDKT
IFALDISSLIAGAKFRGEFEERLKAVLNEIKRSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTL
DEHRKYIEKDPALERRFQPVLVQEPNVEDTISILRGLRERFEIHHGVNIHDRALVAAATLSDRYITDRFLPDKAIDLVDE
ACAMIRTEIDSMPSELDEVTRKVMQLEIEEAALRKETDEASKERLEALQKELADMKEKANSMKVKWMLEKEAIQRVREKR
ETLERLRRELEEAENNYDLNKAAELRHGKIPALEKELKELENEEKEKQGSRLLREEVTEEEIAEIVSRWTGIPISKLVEG
EREKLLRLESILHERVVGQDEAVNLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKALAQSLFDSEDHIIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRNPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSSILLEGTNKDGEITDETKDKVLSQLRGHFRPEFLNRVDEIILFKPLSFEEIKQIVAKLISDLQKRLNDQEIR
LVITNEAQEYIAENGFDPIYGARPLKRFIQRHVETKLAREIVKGSIREQAVVEIGIENGEITLKLRQNETSISGDLTVR

Nucleotide

• Length: 2640 bp

>NTDB_id=122986 BMMGA3_RS04375 WP_004433581.1 877959..880598(+) (clpC) [Bacillus methanolicus MGA3]
ATGGACATTAATCGAATGACAGAACGGTTGCAGCAAGCCTTTTTAAGGGCACAAACATTGGCGACTCAAAATCAGCATCA
GGAAATTGATGATGTACATATATTTTTAGCTCTTTTGGAAGATGAGAATAGCCTAGTTCATTCTATTTTGGAAAAACTTC
AACTTTCTTCAAACGATTTTAAGAATAAACTCGAAAATTTGTTAGCTAAGAAACCGCAAGTCATAGGGAGCGGTGTTGAA
CAAGGAAAAGTTTATATCACTCCTGTTTTACAAAAGGTGTTAGCAGAAGCTGAAACCCAGATGAAGCTTTTTAATGATGA
ATATTTGTCTGTTGAACATATCCTGCTTGCAGCTATTAATACAGAACAGTCAGCAGCAGGTCAAGTGTTAAAAAATTTTC
GGGTCACAATTCAATCGGCATTAGAGGCAATTAAAGAAATTAGGGGGAATCAGAGAGTGACAACACAAAACCCGGAATCT
ACCTATGAAGCATTAAAAAAATACGGAAGAGATTTAGTGGCGGAAGTAAAGGAAGGAAAAATTGACCCAGTTATCGGTAG
AGACAGTGAAATTAGAAATGTCATTCGGATCCTTTCAAGAAAAACGAAAAACAACCCCGTCTTAATCGGTGAACCGGGAG
TAGGAAAAACTGCGATTGTTGAAGGCCTCGCACAGAGAATTGTACGAAAGGATGTTCCAGAGGGACTGAAGGATAAAACC
ATTTTTGCTCTTGATATAAGCTCATTAATCGCAGGGGCCAAATTCCGGGGTGAATTTGAAGAAAGATTGAAAGCTGTATT
AAATGAAATAAAGAGAAGTGAAGGGCGCATCCTTTTGTTTATTGACGAGCTTCATACGATTGTTGGAGCCGGGAAAACAG
AAGGGGCTATGGATGCAGGAAATATGCTGAAACCGATGCTTGCCAGAGGAGAATTGCATTGTATCGGAGCGACAACCCTT
GATGAACATCGGAAATATATTGAAAAGGATCCGGCACTGGAGCGAAGGTTCCAGCCAGTGCTCGTTCAGGAACCAAATGT
TGAAGATACGATTTCAATATTAAGAGGTTTAAGAGAGAGATTTGAAATTCATCATGGAGTCAATATTCATGATCGGGCGC
TCGTTGCTGCTGCTACTCTTTCAGATCGTTATATTACGGACCGTTTTCTTCCCGATAAGGCAATTGATTTGGTGGACGAA
GCATGTGCCATGATCAGGACGGAAATTGACTCGATGCCTTCCGAACTGGACGAAGTAACGCGAAAAGTGATGCAACTAGA
AATTGAAGAGGCTGCATTAAGAAAGGAAACTGATGAAGCAAGTAAAGAGCGGCTGGAAGCTCTTCAAAAAGAATTAGCGG
ATATGAAAGAAAAGGCAAATTCTATGAAAGTGAAGTGGATGTTAGAAAAAGAAGCGATTCAAAGAGTTAGGGAAAAACGT
GAAACACTTGAAAGACTTCGCAGAGAGCTTGAGGAAGCTGAAAATAATTATGATTTAAACAAAGCAGCCGAACTGAGACA
TGGGAAAATTCCTGCTTTGGAAAAAGAATTAAAAGAGCTAGAGAATGAAGAGAAAGAAAAACAGGGAAGCCGATTGCTTA
GAGAAGAAGTTACCGAAGAAGAAATTGCTGAAATTGTTTCACGTTGGACGGGTATTCCAATCTCAAAGCTTGTTGAAGGA
GAAAGAGAGAAACTTCTACGTCTAGAGAGTATTTTACATGAACGAGTAGTTGGACAAGATGAAGCAGTAAACCTTGTATC
AGATGCTGTTTTACGTGCAAGAGCAGGGATTAAAGATCCAAACCGTCCGATCGGATCGTTTATTTTTTTAGGCCCAACTG
GTGTAGGGAAAACAGAGCTTGCTAAAGCTCTTGCCCAGTCATTATTTGATTCGGAAGACCATATTATTCGAATTGATATG
TCTGAATATATGGAGAAACATGCCGTATCACGGTTAATTGGAGCTCCGCCGGGATATGTAGGGTATGAAGAAGGAGGACA
ATTAACAGAAGCTGTAAGAAGAAATCCATATTCAGTTATCCTGTTAGATGAGATTGAAAAAGCGCATCCGGAAGTGTTTA
ATATTTTGTTGCAAATGCTTGATGACGGTCGGATTACTGATTCTCAAGGAAGGACTGTTGATTTTAAGAATACGGTAATC
ATTATGACATCAAATATTGGATCATCTATTCTGCTTGAAGGAACGAATAAAGATGGAGAGATTACAGATGAAACAAAAGA
TAAGGTGTTATCTCAATTGCGTGGTCATTTCCGTCCGGAATTTCTTAACCGTGTTGATGAAATCATTTTATTTAAACCGT
TATCATTTGAAGAAATAAAACAAATTGTAGCAAAACTGATTTCTGACTTACAGAAAAGACTTAACGATCAGGAGATCCGC
TTAGTAATTACAAATGAAGCACAAGAATACATTGCCGAAAATGGTTTTGATCCCATTTATGGAGCAAGACCGCTTAAACG
ATTCATTCAGCGTCATGTTGAAACAAAACTGGCAAGAGAAATTGTCAAAGGAAGCATTAGGGAACAAGCCGTAGTGGAAA
TTGGAATTGAAAATGGAGAAATCACATTAAAACTGAGACAAAATGAAACTTCCATCAGTGGAGACCTCACTGTTCGTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-853)

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

• AAA lid domain (AAA_lid_9) (347-448)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (98-149)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (207-338)

3D structure

• AlphaFold DB: I3E7N7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	48.571	99.545	0.483
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.534	100	0.428
clpC	Lactococcus lactis subsp. cremoris KW2	47.254	78.726	0.372