Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ER12_RS08315 Genome accession   NZ_CP007676
Coordinates   1671913..1672599 (-) Length   228 a.a.
NCBI ID   WP_078103761.1    Uniprot ID   -
Organism   Staphylococcus aureus strain HUV05     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1666913..1677599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ER12_RS08295 (ER12_007890) rpsT 1667827..1668078 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  ER12_RS08300 (ER12_007895) holA 1668123..1669097 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  ER12_RS08305 (ER12_007900) comEC 1669154..1671355 (-) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ER12_RS08310 (ER12_007905) - 1671360..1671821 (-) 462 WP_000439693.1 ComE operon protein 2 -
  ER12_RS08315 (ER12_007910) comEA 1671913..1672599 (-) 687 WP_078103761.1 ComEA family DNA-binding protein Machinery gene
  ER12_RS08320 (ER12_007915) - 1672639..1673355 (-) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  ER12_RS08325 (ER12_007920) rsfS 1673358..1673711 (-) 354 WP_001088022.1 ribosome silencing factor -
  ER12_RS08330 (ER12_007925) yqeK 1673712..1674296 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ER12_RS08335 (ER12_007930) nadD 1674286..1674855 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ER12_RS08340 (ER12_007935) yhbY 1674858..1675148 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  ER12_RS08345 (ER12_007940) aroE 1675152..1675958 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  ER12_RS08350 (ER12_007945) yqeH 1675972..1677072 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25879.54 Da        Isoelectric Point: 9.3305

>NTDB_id=122436 ER12_RS08315 WP_078103761.1 1671913..1672599(-) (comEA) [Staphylococcus aureus strain HUV05]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGLVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=122436 ER12_RS08315 WP_078103761.1 1671913..1672599(-) (comEA) [Staphylococcus aureus strain HUV05]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCTTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

97.797

99.561

0.974
  comEA Staphylococcus aureus N315

96.916

99.561

0.965

Multiple sequence alignment