Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   M0579_RS09640 Genome accession   NZ_CP007668
Coordinates   1906625..1907293 (+) Length   222 a.a.
NCBI ID   WP_025458520.1    Uniprot ID   -
Organism   Neisseria meningitidis M0579     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1906625..1922182 1906625..1907293 within 0


Gene organization within MGE regions


Location: 1906625..1922182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0579_RS09640 (M0579_01790) pilH 1906625..1907293 (+) 669 WP_025458520.1 GspH/FimT family pseudopilin Machinery gene
  M0579_RS09645 (M0579_01791) pilV 1907323..1907934 (+) 612 WP_025458521.1 type IV pilus modification protein PilV Machinery gene
  M0579_RS09650 (M0579_01792) pilJ 1907931..1908917 (+) 987 WP_025458522.1 PilW family protein Machinery gene
  M0579_RS09655 (M0579_01793) pilK 1908896..1909489 (+) 594 WP_002223435.1 pilus assembly PilX family protein Machinery gene
  M0579_RS09660 (M0579_01794) pilX 1909494..1909967 (+) 474 WP_002223437.1 PilX family type IV pilin Machinery gene
  M0579_RS09665 (M0579_01795) dut 1910702..1911154 (+) 453 WP_002222651.1 dUTP diphosphatase -
  M0579_RS09670 (M0579_01796) dapC 1911231..1912418 (+) 1188 WP_002223438.1 succinyldiaminopimelate transaminase -
  M0579_RS16670 - 1912507..1912632 (+) 126 Protein_1818 IS5/IS1182 family transposase -
  M0579_RS09675 (M0579_01797) yaaA 1912681..1913460 (+) 780 WP_002223439.1 peroxide stress protein YaaA -
  M0579_RS09690 (M0579_01800) - 1914017..1915213 (+) 1197 WP_002223440.1 tyrosine-type recombinase/integrase -
  M0579_RS09695 (M0579_01801) - 1915370..1915750 (+) 381 WP_002220683.1 type II toxin-antitoxin system PemK/MazF family toxin -
  M0579_RS09710 (M0579_01802) - 1916298..1916654 (+) 357 WP_002223441.1 DUF4760 domain-containing protein -
  M0579_RS09715 (M0579_01803) - 1917523..1918440 (+) 918 WP_002219437.1 KilA-N domain-containing protein -
  M0579_RS09720 (M0579_01804) - 1918498..1918707 (-) 210 WP_002220687.1 hypothetical protein -
  M0579_RS09725 (M0579_01805) - 1918704..1918844 (-) 141 WP_002223442.1 hypothetical protein -
  M0579_RS09730 (M0579_01806) - 1918844..1919035 (-) 192 WP_002219435.1 type ISP restriction/modification enzyme -
  M0579_RS09735 (M0579_01807) - 1919038..1919331 (-) 294 WP_002220689.1 hypothetical protein -
  M0579_RS09740 (M0579_01808) - 1919328..1919588 (-) 261 WP_002223443.1 NGO1622 family putative holin -
  M0579_RS09745 (M0579_01809) - 1919623..1919838 (-) 216 WP_002219434.1 hypothetical protein -
  M0579_RS09750 (M0579_01810) - 1919908..1920762 (-) 855 WP_002219433.1 YfdQ family protein -
  M0579_RS09755 (M0579_01811) - 1920787..1921146 (-) 360 WP_002219432.1 hypothetical protein -
  M0579_RS09760 (M0579_01812) - 1921214..1921414 (-) 201 WP_002219431.1 hypothetical protein -
  M0579_RS09765 (M0579_01813) - 1921658..1922083 (-) 426 WP_002219430.1 hypothetical protein -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24750.27 Da        Isoelectric Point: 9.7663

>NTDB_id=122252 M0579_RS09640 WP_025458520.1 1906625..1907293(+) (pilH) [Neisseria meningitidis M0579]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKGGAPN
NKCDFGKKGQGMLAFGDKNGNKTYDGDTADVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYTN
DQHLTSQSSFSYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRTVCQYK

Nucleotide


Download         Length: 669 bp        

>NTDB_id=122252 M0579_RS09640 WP_025458520.1 1906625..1907293(+) (pilH) [Neisseria meningitidis M0579]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCATGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGAGAAGCCGTCCGGCTCAATCTTCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGGCGGTGCGCCCAAC
AATAAATGTGACTTCGGCAAGAAGGGGCAGGGAATGTTGGCTTTTGGCGATAAGAATGGCAATAAGACATATGACGGCGA
TACGGCGGATGTTCTCCTTCGCAGTGTGGTATTGAATGATGATATCAATGATAAGCGGATTAATTATGCCTTTAACCATA
TCGCTTTCGGTCAAACGCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAC
GACCAGCATCTTACAAGCCAATCCAGCTTTTCTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACG
ATAGGCGTACCGTATGCCAATATAAATGA

Domains

Predicted by InterproScan.

Type II transport protein GspH (GspH)

(44-205)

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

85.068

99.55

0.847

Multiple sequence alignment