Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   M0579_RS03535 Genome accession   NZ_CP007668
Coordinates   747109..747969 (+) Length   286 a.a.
NCBI ID   WP_002223365.1    Uniprot ID   -
Organism   Neisseria meningitidis M0579     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 742109..752969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0579_RS03515 (M0579_00654) dapD 742619..743440 (-) 822 WP_002216408.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
  M0579_RS03520 - 743450..743680 (-) 231 WP_025458514.1 hypothetical protein -
  M0579_RS03525 (M0579_00655) pgi 743650..745293 (-) 1644 WP_002223366.1 glucose-6-phosphate isomerase -
  M0579_RS03530 (M0579_00656) pilG 745803..747035 (+) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  M0579_RS03535 (M0579_00657) pilD 747109..747969 (+) 861 WP_002223365.1 prepilin peptidase Machinery gene
  M0579_RS03540 (M0579_00658) coaE 747971..748603 (+) 633 WP_002223363.1 dephospho-CoA kinase -
  M0579_RS03545 (M0579_00659) - 748596..748805 (+) 210 WP_002212333.1 DNA gyrase inhibitor YacG -
  M0579_RS03550 (M0579_00660) pilF 748890..750566 (-) 1677 WP_002221967.1 type IV-A pilus assembly ATPase PilB Machinery gene
  M0579_RS03560 (M0579_00662) - 751058..751504 (-) 447 WP_002220271.1 DUF441 domain-containing protein -
  M0579_RS03565 (M0579_00663) ispB 751509..752483 (-) 975 WP_002220270.1 octaprenyl diphosphate synthase -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31363.39 Da        Isoelectric Point: 8.2213

>NTDB_id=122226 M0579_RS03535 WP_002223365.1 747109..747969(+) (pilD) [Neisseria meningitidis M0579]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLIAWQYGWSWITLGGLVLTAFLISLTFIDADTQYLPDSMTLL
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGETGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=122226 M0579_RS03535 WP_002223365.1 747109..747969(+) (pilD) [Neisseria meningitidis M0579]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGTCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGATCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGAT
TGGTACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCTC
TTGATTTGGCTGGGACTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(134-242)

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

95.439

99.65

0.951
  pilD Vibrio cholerae strain A1552

44.444

100

0.448
  pilD Vibrio campbellii strain DS40M4

44.928

96.503

0.434
  pilD Acinetobacter baumannii D1279779

46.591

92.308

0.43
  pilD Acinetobacter nosocomialis M2

46.591

92.308

0.43

Multiple sequence alignment