Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EN73_RS06330 Genome accession   NZ_CP007632
Coordinates   1241483..1242709 (-) Length   408 a.a.
NCBI ID   WP_000918415.1    Uniprot ID   A0A0H1T4M5
Organism   Streptococcus agalactiae strain NGBS572     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1236483..1247709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN73_RS06305 (EN73_06425) - 1237357..1238733 (-) 1377 WP_000427485.1 amino acid permease -
  EN73_RS06310 (EN73_06430) - 1238863..1239513 (-) 651 WP_000120093.1 HXXEE domain-containing protein -
  EN73_RS10640 - 1239671..1240174 (-) 504 WP_000645480.1 HXXEE domain-containing protein -
  EN73_RS06320 (EN73_06440) - 1240266..1240814 (+) 549 WP_000140662.1 TetR/AcrR family transcriptional regulator -
  EN73_RS06325 (EN73_06445) yihA 1240876..1241472 (-) 597 WP_000796925.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EN73_RS06330 (EN73_06450) clpX 1241483..1242709 (-) 1227 WP_000918415.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EN73_RS06340 (EN73_06460) - 1242927..1243421 (-) 495 WP_000166043.1 dihydrofolate reductase -
  EN73_RS06345 (EN73_06465) - 1243501..1244340 (-) 840 WP_000158595.1 thymidylate synthase -
  EN73_RS06350 (EN73_06470) - 1244494..1245666 (+) 1173 WP_001874012.1 hydroxymethylglutaryl-CoA synthase -
  EN73_RS06355 (EN73_06475) - 1245668..1246951 (+) 1284 WP_000161690.1 hydroxymethylglutaryl-CoA reductase, degradative -
  EN73_RS06360 (EN73_06480) - 1247043..1247492 (+) 450 WP_001039194.1 DUF1836 domain-containing protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44836.25 Da        Isoelectric Point: 4.4424

>NTDB_id=121902 EN73_RS06330 WP_000918415.1 1241483..1242709(-) (clpX) [Streptococcus agalactiae strain NGBS572]
MAGNRNNDMNVYCSFCGKSQDEVKKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLEILNQYVVGQDR
AKRALAVAVYNHYKRVSYTESSDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTKN
ILFIVGGAFDGIEDLVKQRLGEKVIGFGQTSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALELLTAEDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALLAIADKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGT
DKPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=121902 EN73_RS06330 WP_000918415.1 1241483..1242709(-) (clpX) [Streptococcus agalactiae strain NGBS572]
ATGGCTGGGAATCGTAATAACGATATGAATGTCTATTGTTCATTTTGTGGCAAAAGCCAAGATGAAGTAAAAAAAATTAT
TGCAGGTAATGGTGTTTTCATTTGTAATGAATGTGTGGCCTTATCACAAGAAATTATTAAGGAAGAATTAGCTGAGGAAG
TACTGGCTGATTTAGCAGAAGTACCAAAACCTAAGGAACTATTAGAAATATTAAATCAATATGTTGTAGGGCAAGATCGT
GCTAAACGTGCTTTAGCAGTTGCTGTCTACAATCATTACAAGCGTGTTAGTTATACCGAGAGTAGTGACGATGATGTAGA
TTTGCAAAAATCCAACATTTTGATGATTGGTCCAACTGGCTCAGGAAAAACCTTCTTAGCACAAACACTGGCTAAAAGCC
TTAATGTACCGTTTGCTATTGCAGATGCGACTTCATTGACCGAAGCAGGATACGTTGGAGAAGATGTTGAGAATATTCTT
CTTAAATTGATTCAAGCTGCTGATTATAATGTCGAACGTGCTGAGCGTGGTATTATCTACGTTGATGAAATAGATAAAAT
TGCTAAGAAAGGCGAAAATGTTTCTATCACACGTGATGTGTCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTATTG
AGGGTACGGTAGCAAGTGTTCCCCCACAGGGTGGGCGTAAACATCCTAACCAAGAAATGATTCAAATTAATACCAAGAAC
ATCCTTTTTATTGTCGGTGGTGCTTTTGATGGTATTGAAGACCTTGTGAAGCAACGTTTAGGCGAAAAAGTTATTGGTTT
TGGACAGACAAGCCGTAAAATTGATGACAACGCTTCTTATATGCAAGAGATAATTTCTGAGGATATTCAAAAGTTTGGAC
TGATTCCAGAGTTTATTGGCCGTTTACCAGTAGTTGCAGCGTTAGAACTTCTTACTGCAGAAGATCTGGTTCGTATTCTG
ACAGAACCACGCAATGCTTTGGTTAAACAATACCAAACCTTATTATCTTATGATGGTGTAGAATTGGAATTTGACCAGGA
TGCTCTATTGGCTATCGCTGATAAGGCTATCGAGCGCAAGACTGGTGCACGTGGTTTACGTTCTATTATTGAAGAAACGA
TGCTTGATATCATGTTTGAAATTCCAAGCCAAGAAGATGTAACAAAAGTTCGTATCACAAAGGCTGCTGTTGAGGGTACT
GACAAGCCTGTTTTAGAGACGGCTTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H1T4M5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

90.465

100

0.907
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.25

98.039

0.571

Multiple sequence alignment