Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   EN73_RS03915 Genome accession   NZ_CP007632
Coordinates   725898..727247 (+) Length   449 a.a.
NCBI ID   WP_001065465.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NGBS572     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 720898..732247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN73_RS03885 (EN73_04015) - 721303..721869 (+) 567 WP_000592389.1 PepSY domain-containing protein -
  EN73_RS03890 (EN73_04020) - 721918..722568 (-) 651 WP_000100034.1 amino acid ABC transporter permease -
  EN73_RS03895 (EN73_04025) - 722580..723275 (-) 696 WP_000173638.1 amino acid ABC transporter permease -
  EN73_RS03900 (EN73_04030) - 723288..724088 (-) 801 WP_000946173.1 transporter substrate-binding domain-containing protein -
  EN73_RS03905 (EN73_04035) - 724100..724855 (-) 756 WP_000053146.1 amino acid ABC transporter ATP-binding protein -
  EN73_RS03910 (EN73_04040) vicR 725195..725905 (+) 711 WP_000722052.1 response regulator YycF Regulator
  EN73_RS03915 (EN73_04045) vicK 725898..727247 (+) 1350 WP_001065465.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EN73_RS03920 (EN73_04050) vicX 727251..728060 (+) 810 WP_001289498.1 MBL fold metallo-hydrolase Regulator
  EN73_RS03925 (EN73_04055) - 728063..728431 (+) 369 WP_000719384.1 YbaN family protein -
  EN73_RS03930 (EN73_04060) rnc 728606..729292 (+) 687 WP_000661526.1 ribonuclease III -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51060.11 Da        Isoelectric Point: 4.8106

>NTDB_id=121889 EN73_RS03915 WP_001065465.1 725898..727247(+) (vicK) [Streptococcus agalactiae strain NGBS572]
MNNSAANIRSFELALLFLLVFVAVYFVYLAVRDFKMSKDIRLLNWKVRDLIAGNYSDSILIQGDADLVELGESLNDLSDV
FRMAHDNLEQEKNRLASILTYMTDGVLATDRSGKIVMINETAQQQFNLAYDEALSMNIVDMLGSGSPYSFQDLVSKTPEV
VLNRRDENGEFVTLRIRFALNRRESGFISGLVAVSHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALNE
EVAPSFIKVSLDETNRMMRMISDLLSLSRIDNEVTHLDVEMTNFTAFMTSILNRFDQIRNQKTVTGKVYEIVRDYPLKSI
WVEIDTDKMTQVIDNILNNAVKYSPDGGKITVNLRTTKTQMILSISDQGLGIPKKDLPLIFDRFYRVDKARSRQQGGTGL
GLSIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVTYEEWEDVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=121889 EN73_RS03915 WP_001065465.1 725898..727247(+) (vicK) [Streptococcus agalactiae strain NGBS572]
ATGAATAATAGTGCTGCAAATATTAGGTCGTTTGAGCTAGCCTTACTTTTTTTACTAGTTTTTGTTGCTGTCTATTTTGT
TTATCTAGCGGTTAGAGATTTTAAAATGTCTAAAGATATCCGGCTTTTGAATTGGAAAGTCAGAGATTTGATAGCAGGAA
ATTATTCAGATAGTATTCTAATTCAAGGTGATGCAGATTTGGTAGAATTAGGGGAAAGTCTAAATGATTTATCTGATGTC
TTCCGAATGGCACATGATAACTTAGAACAAGAAAAGAATCGCTTAGCGAGTATCTTAACTTATATGACTGACGGTGTGCT
GGCTACAGATCGTTCAGGAAAAATCGTTATGATTAATGAGACAGCCCAACAGCAGTTCAATCTAGCATATGATGAAGCTT
TATCAATGAATATTGTTGATATGTTAGGGTCGGGAAGTCCATATTCGTTCCAAGATTTAGTCTCTAAGACGCCAGAGGTA
GTTCTTAATAGACGTGATGAAAATGGTGAATTTGTTACCTTACGGATTCGATTTGCTTTGAACCGTCGTGAAAGTGGTTT
TATTTCCGGTTTAGTTGCAGTATCACACGATGCTACTGAGCAAGAGAAAGAAGAGCGTGAAAGAAGACTTTTTGTATCTA
ATGTTTCTCATGAACTTCGTACACCTTTGACATCTGTAAAATCTTATTTAGAAGCTTTAGATGAGGGAGCGCTCAATGAA
GAAGTTGCTCCAAGCTTCATTAAGGTATCTCTAGATGAAACAAATCGTATGATGCGTATGATATCAGATTTATTAAGTTT
ATCGCGCATTGATAATGAAGTAACGCATTTAGATGTTGAAATGACGAATTTTACAGCTTTCATGACCTCAATTTTGAATC
GATTTGATCAGATTAGAAATCAAAAAACAGTCACAGGAAAAGTTTATGAAATTGTCAGAGATTATCCTCTTAAGTCAATT
TGGGTGGAAATTGATACAGATAAGATGACTCAAGTGATTGATAACATTTTAAATAATGCAGTCAAGTATTCACCAGATGG
TGGTAAGATTACAGTTAATCTACGCACAACTAAAACGCAGATGATTTTATCAATATCAGACCAAGGCTTAGGTATTCCCA
AAAAAGATTTACCTCTCATTTTTGATCGTTTTTATCGTGTTGATAAGGCGAGAAGTCGTCAACAGGGTGGGACTGGACTT
GGTTTGTCAATTGCAAAAGAAATTGTTAAGCAGCATAAGGGATTTATTTGGGCTAAGAGTGAGTATGGTAAAGGGTCTAC
TTTTACAATCGTCTTGCCTTATGATAAAGATGCTGTAACTTATGAAGAATGGGAGGACGTTGAAGATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-180)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.576

91.982

0.686
  micB Streptococcus pneumoniae Cp1015

67.765

94.655

0.641

Multiple sequence alignment