Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   RC12_RS05880 Genome accession   NZ_CP010460
Coordinates   1113387..1114052 (-) Length   221 a.a.
NCBI ID   WP_002853205.1    Uniprot ID   Q0P933
Organism   Campylobacter jejuni strain CJ677CC058     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1108387..1119052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RC12_RS05865 (RC12_05875) groES 1110243..1110503 (+) 261 WP_002825273.1 co-chaperone GroES -
  RC12_RS05870 (RC12_05880) groL 1110524..1112161 (+) 1638 WP_002933798.1 chaperonin GroEL -
  RC12_RS05875 (RC12_05885) dccS 1112204..1113394 (-) 1191 WP_002933796.1 two-component system sensor histidine kinase DccS -
  RC12_RS05880 (RC12_05890) ciaR 1113387..1114052 (-) 666 WP_002853205.1 two-component system response regulator DccR Regulator
  RC12_RS05885 (RC12_05895) - 1114200..1114799 (+) 600 WP_002866222.1 bacteriohemerythrin -
  RC12_RS05890 (RC12_05900) - 1114811..1115059 (+) 249 WP_002892742.1 ribbon-helix-helix domain-containing protein -
  RC12_RS05900 (RC12_05910) - 1115316..1116563 (-) 1248 WP_002853920.1 ArsS family sensor histidine kinase -
  RC12_RS05905 (RC12_05915) - 1116560..1117234 (-) 675 WP_002777451.1 response regulator transcription factor -
  RC12_RS05910 (RC12_05920) htrA 1117310..1118728 (-) 1419 WP_002933713.1 serine protease HtrA -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25633.32 Da        Isoelectric Point: 4.6834

>NTDB_id=121607 RC12_RS05880 WP_002853205.1 1113387..1114052(-) (ciaR) [Campylobacter jejuni strain CJ677CC058]
MAAKILLLEDDLSLSEIIEEFLNDEGYEVFLCDNAQEALDMAYERYFDLWILDVKVPLGDGFSLLKELRKSGKQTPAIFM
TSLNTTNDLKQGFDAGCDDYIKKPFELAELSIRVKALLKRAFSHKNEDFEDLGDGFRFEFTTQILYHNNKALTLPSKEIK
LLSLLLKNKNNFLSTERIFEELWDYDEEPSELSLRAYVKNLRKILGKEKIINQRGRGYCYG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=121607 RC12_RS05880 WP_002853205.1 1113387..1114052(-) (ciaR) [Campylobacter jejuni strain CJ677CC058]
ATGGCTGCTAAAATTTTACTTTTAGAAGATGATTTGAGCTTGAGTGAGATCATTGAAGAGTTTTTAAACGATGAAGGATA
TGAAGTATTTTTATGCGATAATGCACAAGAAGCTTTAGATATGGCTTATGAAAGATATTTTGATCTTTGGATTTTAGATG
TAAAAGTTCCTTTAGGAGATGGATTTTCATTACTTAAAGAATTAAGAAAAAGCGGAAAGCAAACTCCAGCAATTTTCATG
ACTTCTTTAAACACAACAAACGATTTAAAACAAGGCTTTGATGCAGGTTGTGATGATTATATAAAAAAACCTTTTGAACT
TGCCGAGTTATCTATCAGGGTTAAAGCTTTGCTTAAAAGAGCTTTTTCACATAAAAATGAAGATTTTGAAGATTTAGGAG
ATGGATTTAGATTTGAATTTACTACACAAATTCTTTACCATAATAATAAAGCCTTGACTTTACCGAGTAAAGAAATTAAG
CTTTTGTCTTTATTACTTAAAAATAAAAACAACTTTTTAAGCACAGAGAGAATTTTTGAAGAACTCTGGGATTATGATGA
GGAGCCTAGTGAGCTAAGTTTAAGGGCTTATGTGAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAATCAAA
GAGGCAGGGGATATTGCTATGGCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0P933

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae D39

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae R6

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae TIGR4

36.364

99.548

0.362

Multiple sequence alignment