Detailed information NTG0121593

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EG66_RS03410
• Genome accession: NZ_CP007605
• Coordinates: 669533..670333 (+)
• Length: 266 a.a.
• NCBI ID: WP_023591965.1
• Uniprot ID: V5NN53
• Organism: Helicobacter pylori strain BM012B
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 664533..675333

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EG66_RS03375 (EG66_03555)	pseH	665027..665569 (+)	543	WP_023591961.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-
EG66_RS03380 (EG66_03560)	-	665502..666440 (-)	939	WP_023591962.1	tetraacyldisaccharide 4'-kinase	-
EG66_RS03385 (EG66_03565)	-	666437..667219 (-)	783	WP_023591963.1	NAD+ synthase	-
EG66_RS03395 (EG66_03575)	ilvC	667469..668461 (+)	993	WP_023591964.1	ketol-acid reductoisomerase	-
EG66_RS03400 (EG66_03580)	minD	668485..669291 (+)	807	WP_023526244.1	septum site-determining protein MinD	-
EG66_RS03405 (EG66_03585)	minE	669288..669521 (+)	234	WP_000118278.1	cell division topological specificity factor MinE	-
EG66_RS03410 (EG66_03590)	dprA	669533..670333 (+)	801	WP_023591965.1	DNA-processing protein DprA	Machinery gene
EG66_RS03415 (EG66_03595)	dprB	670330..670734 (+)	405	WP_038419820.1	Holliday junction resolvase RuvX	Machinery gene
EG66_RS03420	-	670793..671143 (+)	351	WP_049828088.1	tetratricopeptide repeat protein	-
EG66_RS08350	-	671121..671618 (+)	498	Protein_650	hypothetical protein	-
EG66_RS08860	-	671621..671824 (+)	204	WP_080261063.1	hypothetical protein	-
EG66_RS08865	-	671836..672534 (+)	699	WP_226975758.1	DUF1887 domain-containing protein	-
EG66_RS08360	-	672784..672906 (+)	123	Protein_653	type II restriction endonuclease	-
EG66_RS08730 (EG66_03615)	-	673057..673271 (-)	215	Protein_654	hypothetical protein	-
EG66_RS03445	-	673317..673505 (-)	189	WP_023591972.1	hypothetical protein	-
EG66_RS03450 (EG66_03625)	mscS	673558..674381 (-)	824	Protein_656	small-conductance mechanosensitive channel MscS	-
EG66_RS08655	-	674531..674651 (-)	121	Protein_657	DNA adenine methylase	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29955.83 Da
• Isoelectric Point: 8.3904

>NTDB_id=121593 EG66_RS03410 WP_023591965.1 669533..670333(+) (dprA) [Helicobacter pylori strain BM012B]
MKSHFQYSALENIPKAFDTLKDPPKKLYCVGDTKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGTVIVSGGALGV
DIIAQENALPKTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDVVIIPQADLQSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDYHLKEMPEMKDEFLEYFAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHLVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=121593 EG66_RS03410 WP_023591965.1 669533..670333(+) (dprA) [Helicobacter pylori strain BM012B]
ATGAAAAGCCACTTCCAATACAGCGCGCTAGAAAATATCCCTAAAGCCTTTGATACGCTCAAAGACCCCCCTAAAAAACT
CTATTGTGTGGGCGACACCAAGCTTTTAGAAGCGCCTTTAAAAGTGGCTATCATAGGCACAAGAAGACCCACCCCTTACA
GCAAGCAACACACGATCACTCTAGCCAGAGAGCTTGCTAAAAATGGCACGGTTATTGTGAGTGGGGGAGCGTTAGGAGTG
GATATTATCGCTCAAGAAAACGCCTTACCAAAAACGATCATGCTTTCGCCTTGCAGTTTGGATTTCATCTATCCTACGAA
CAACCATAAAGTGATCCAAGAAATCGCGCAAAACGGCCTGATTTTAAGCGAATATGAAAAAGACTTCATGCCCATTAAAG
GCTCTTTTTTAGCGAGAAACCGCCTAGTGATCGCTTTAAGCGATGTAGTGATTATCCCCCAAGCGGATTTACAAAGCGGC
TCTATGAGTAGCGCGAGATTAGCCCAAAAATACCAAAAACCCTTATTTGTTTTGCCTCAACGCCTGAATGAGAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGACT
ACCATTTAAAAGAAATGCCTGAAATGAAAGATGAATTTTTAGAATATTTTGCGAAAAACCCTAGCTATGAAGAGGCGTAT
CTCAAATTTGGGGATAAACTTTTAGAATACGAGCTGTTGGGTAAGATCAAGCGCATCAATCATCTCGTGGTGTTAGCGTG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (11-197)

3D structure

• AlphaFold DB: V5NN53

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	96.617	100	0.966
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	47.345	84.962	0.402