Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   EG63_RS00220 Genome accession   NZ_CP007604
Coordinates   37575..38318 (+) Length   247 a.a.
NCBI ID   WP_038417115.1    Uniprot ID   -
Organism   Helicobacter pylori strain BM013A     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32575..43318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EG63_RS00195 (EG63_00200) panD 34733..35086 (+) 354 WP_038417112.1 aspartate 1-decarboxylase -
  EG63_RS00200 (EG63_00205) - 35089..35391 (+) 303 WP_000347928.1 YbaB/EbfC family nucleoid-associated protein -
  EG63_RS00205 (EG63_00210) - 35391..36386 (+) 996 WP_038417113.1 PDZ domain-containing protein -
  EG63_RS00210 (EG63_00215) comB6 36394..37449 (+) 1056 WP_038417114.1 P-type conjugative transfer protein TrbL Machinery gene
  EG63_RS00215 comB7 37465..37578 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  EG63_RS00220 (EG63_00225) comB8 37575..38318 (+) 744 WP_038417115.1 type IV secretion system protein Machinery gene
  EG63_RS00225 (EG63_00230) comB9 38318..39289 (+) 972 WP_038417116.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  EG63_RS00230 (EG63_00235) comB10 39282..40418 (+) 1137 WP_038417117.1 DNA type IV secretion system protein ComB10 Machinery gene
  EG63_RS00235 (EG63_00240) - 40488..41906 (+) 1419 WP_038417118.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  EG63_RS00240 (EG63_00245) gmd 41931..43076 (+) 1146 WP_038417119.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28725.92 Da        Isoelectric Point: 8.9604

>NTDB_id=121563 EG63_RS00220 WP_038417115.1 37575..38318(+) (comB8) [Helicobacter pylori strain BM013A]
MKEKPFNSEQLNYLEELLSHQEKHLENRLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISGNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
VPTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=121563 EG63_RS00220 WP_038417115.1 37575..38318(+) (comB8) [Helicobacter pylori strain BM013A]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGAACTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAGGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGATTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTCCTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAATCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTGGTAA
TGAAGCGTTGGCCAGATCGCTTATAGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTTCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGTGT
CTCTATTGCGGCTAAACTCATGAATGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GTGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

95.951

100

0.96

Multiple sequence alignment