Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ayp1020_RS05700 Genome accession   NZ_CP007601
Coordinates   1191080..1191709 (-) Length   209 a.a.
NCBI ID   WP_002469716.1    Uniprot ID   -
Organism   Staphylococcus capitis subsp. capitis strain AYP1020     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1186080..1196709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ayp1020_RS05670 (AYP1020_1156) - 1186435..1186965 (-) 531 WP_047796449.1 acyl-CoA thioesterase -
  ayp1020_RS05675 (AYP1020_1157) - 1187068..1188309 (-) 1242 WP_047796450.1 aminopeptidase -
  ayp1020_RS05680 (AYP1020_1158) - 1188323..1188529 (-) 207 WP_002435959.1 DUF1128 domain-containing protein -
  ayp1020_RS05685 (AYP1020_1159) - 1188670..1189134 (+) 465 WP_047796451.1 low molecular weight protein-tyrosine-phosphatase -
  ayp1020_RS05690 (AYP1020_1160) - 1189141..1189425 (+) 285 WP_002435890.1 hypothetical protein -
  ayp1020_RS05695 (AYP1020_1161) - 1189762..1191015 (+) 1254 WP_002435884.1 YihY/virulence factor BrkB family protein -
  ayp1020_RS05700 (AYP1020_1162) vraR 1191080..1191709 (-) 630 WP_002469716.1 two-component system response regulator VraR Regulator
  ayp1020_RS05705 (AYP1020_1163) vraS 1191699..1192745 (-) 1047 WP_002435929.1 sensor histidine kinase Regulator
  ayp1020_RS05710 (AYP1020_1164) liaF 1192742..1193443 (-) 702 WP_047796452.1 cell wall-active antibiotics response protein LiaF -
  ayp1020_RS05715 (AYP1020_1165) - 1193458..1193844 (-) 387 WP_002453601.1 hypothetical protein -
  ayp1020_RS05720 (AYP1020_1166) map 1193989..1194744 (-) 756 WP_047796453.1 type I methionyl aminopeptidase -
  ayp1020_RS05725 (AYP1020_1167) - 1194918..1195907 (+) 990 WP_002435886.1 FUSC family protein -
  ayp1020_RS05730 (AYP1020_1168) isaB 1195985..1196527 (-) 543 WP_023350030.1 immunodominant staphylococcal antigen IsaB family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23645.28 Da        Isoelectric Point: 4.8997

>NTDB_id=121519 ayp1020_RS05700 WP_002469716.1 1191080..1191709(-) (vraR) [Staphylococcus capitis subsp. capitis strain AYP1020]
MAIKVLFVDDHEMVRIGISSYLSTQQDIEVVGEGASGKEAIEKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPHIRVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIADAVRKTYQGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=121519 ayp1020_RS05700 WP_002469716.1 1191080..1191709(-) (vraR) [Staphylococcus capitis subsp. capitis strain AYP1020]
ATGGCGATTAAAGTATTGTTTGTTGATGACCATGAAATGGTTAGAATTGGTATTTCAAGCTATCTATCTACACAACAGGA
TATTGAAGTAGTTGGAGAAGGTGCTTCTGGTAAAGAAGCTATCGAAAAAGCCCATGAGTTGAAACCAGATTTAATTTTAA
TGGATTTACTTATGGATGATATGGATGGTGTAGAAGCTACTACTGAAATTAAAAAGGATTTACCTCACATAAGAGTAGTA
ATGTTAACAAGCTTTATCGAGGATAAAGAAGTTTATCGAGCATTAGATGCTGGGGTAGATAGTTATATCTTAAAAACGAC
TAGTGCGAGTGACATTGCTGACGCAGTACGTAAAACATATCAAGGGGAATCTGTTTTTGAACCAGAAGTACTTGTAAAAA
TGAGAAACCGCATGAAAAAACGTGCTGAGTTATATGAAATGCTTACAGAGCGTGAAATGGAAATTTTATTATTAATTGCC
AAAGGTTACTCTAACCAAGAAATTGCTAGCGCCTCTCATATCACTATTAAAACTGTTAAAACACACGTAAGTAATATATT
GAGTAAGTTAGAAGTTCAAGATAGAACTCAAGCTGTTATTTATGCTTTCCAACATAATTTGATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364

Multiple sequence alignment