Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DK43_RS06075 Genome accession   NZ_CP007573
Coordinates   1257929..1259161 (-) Length   410 a.a.
NCBI ID   WP_003027977.1    Uniprot ID   I0SHV1
Organism   Streptococcus anginosus strain SA1     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1250033..1265279 1257929..1259161 within 0


Gene organization within MGE regions


Location: 1250033..1265279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK43_RS06045 (DK43_06225) - 1250033..1250773 (+) 741 WP_003024883.1 amino acid ABC transporter ATP-binding protein -
  DK43_RS06050 (DK43_06230) - 1251297..1252832 (+) 1536 WP_003027982.1 ABC-F family ATP-binding cassette domain-containing protein -
  DK43_RS06055 (DK43_06235) - 1252853..1254601 (-) 1749 WP_003027981.1 ABC transporter ATP-binding protein -
  DK43_RS06060 (DK43_06240) - 1254582..1256327 (-) 1746 WP_022525343.1 ABC transporter ATP-binding protein -
  DK43_RS06065 (DK43_06245) - 1256500..1257207 (-) 708 WP_003027979.1 glucosaminidase domain-containing protein -
  DK43_RS06070 (DK43_06250) yihA 1257330..1257917 (-) 588 WP_003027978.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DK43_RS06075 (DK43_06255) clpX 1257929..1259161 (-) 1233 WP_003027977.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DK43_RS10435 (DK43_06260) - 1259200..1259373 (-) 174 WP_003024903.1 hypothetical protein -
  DK43_RS06085 (DK43_06265) - 1259373..1259885 (-) 513 WP_003027976.1 dihydrofolate reductase -
  DK43_RS06090 (DK43_06270) - 1260070..1260909 (-) 840 WP_003027975.1 thymidylate synthase -
  DK43_RS06095 (DK43_06275) - 1260997..1262214 (-) 1218 WP_003027974.1 chloride channel protein -
  DK43_RS06100 (DK43_06280) - 1262229..1262495 (-) 267 WP_003027973.1 chorismate mutase -
  DK43_RS10140 (DK43_06285) - 1262940..1264174 (-) 1235 Protein_1216 aminoacyltransferase -
  DK43_RS06115 (DK43_06290) - 1264336..1265279 (-) 944 Protein_1217 IS30 family transposase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45688.21 Da        Isoelectric Point: 4.4242

>NTDB_id=121210 DK43_RS06075 WP_003027977.1 1257929..1259161(-) (clpX) [Streptococcus anginosus strain SA1]
MPTNRTNEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNREDEEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDETGSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVDDLVR
ILREPKNALVKQYQTLLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=121210 DK43_RS06075 WP_003027977.1 1257929..1259161(-) (clpX) [Streptococcus anginosus strain SA1]
ATGCCTACAAATCGTACAAACGAAATGATGGTTTATTGTTCTTTTTGTGGTAAAAGCCAAGAAGAAGTGCAAAAGATCAT
CGCAGGAAATAATGCCTTTATTTGTAATGAATGTGTGGAATTAGCACAAGAAATCATCAGAGAGGAACTAGCAGAAGAAG
TGCTAGCAGACTTGTCAGAAGTGCCAAAACCACAAGAACTACTCAATATTTTGAATCACTATGTGATTGGACAAGACCGT
GCTAAGCGTGCTTTGGCTGTGGCTGTCTACAATCACTATAAACGCATCAATTTTCATGATAATCGTGAAGATGAGGAAGA
TGTCGAATTGCAGAAATCCAATATCCTTATGATTGGTCCAACTGGTTCTGGCAAGACCTTCCTCGCTCAAACTTTAGCAA
AAAGTCTGAATGTTCCTTTTGCGATTGCAGATGCGACAGCTTTGACAGAAGCTGGGTATGTCGGAGAAGATGTTGAAAAT
ATTCTCTTGAAACTCTTGCAAGCAGCAGATTTCAATATTGAGCGTGCTGAACGTGGTATCATCTATGTAGATGAGATTGA
CAAAATTGCGAAGAAAAGCGAAAATGTCTCTATTACTCGTGATGTGTCTGGTGAAGGTGTTCAGCAAGCACTCCTCAAGA
TTATTGAAGGAACTGTAGCTAGCGTACCTCCGCAAGGCGGCCGCAAGCATCCTCAACAAGAGATGATTCAAGTAGATACG
AAAAATATTCTCTTTATCGTTGGTGGTGCATTTGACGGTATTGAAGAAATTGTCAAACAACGTCTAGGCGAAAAAATTAT
CGGTTTTGGTCAAAACAACAAAGCCATTGATGAAACTGGTTCTTATATGCAAGAAATCATCTCTGAAGATATTCAAAAAT
TTGGCTTGATTCCTGAATTGATTGGTCGTTTGCCTGTATTTGCAGCGCTTGAGCCTTTAACAGTTGATGATTTGGTGCGA
ATCCTTCGCGAACCAAAGAATGCTTTAGTGAAGCAATATCAGACTCTTCTTTCTTATGATGATGTCAAATTGGAGTTTGA
TGATGATGCTCTTCAGGAAATCGCTAACAAGGCCATTGAACGCAAGACAGGTGCGCGTGGATTACGTTCGATTATCGAGG
AAACTATGATGGATGTCATGTTTGAAGTTCCAAGTCAAGAAAATGTGAAGCTGGTACGGATTACCAAGGAAGCAGTTGAC
GGAACGGATAAGCCGATTTTAGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SHV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.829

100

0.868
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.458

98.049

0.573

Multiple sequence alignment