Detailed information NTG0120904

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DK92_RS06650
• Genome accession: NZ_CP007561
• Coordinates: 1358924..1359925 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NGAS596
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1353924..1364925

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK92_RS06635 (DK92_06815)	thrS	1354095..1356038 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
DK92_RS06640 (DK92_06825)	-	1356460..1357794 (-)	1335	WP_047235925.1	glycosyltransferase family 4 protein	-
DK92_RS06645 (DK92_06830)	-	1357796..1358794 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DK92_RS06650 (DK92_06835)	ccpA	1358924..1359925 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DK92_RS06655 (DK92_06840)	-	1360099..1361184 (+)	1086	WP_047235926.1	aminopeptidase P family protein	-
DK92_RS06660 (DK92_06845)	-	1361233..1361898 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DK92_RS06665 (DK92_06850)	-	1361909..1362286 (+)	378	WP_047235927.1	VOC family protein	-
DK92_RS06670 (DK92_06855)	-	1362431..1363357 (+)	927	WP_047235928.1	glycosyltransferase family 2 protein	-
DK92_RS06675 (DK92_06860)	-	1363566..1364249 (+)	684	WP_012560521.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=120904 DK92_RS06650 WP_002985680.1 1358924..1359925(-) (ccpA) [Streptococcus pyogenes strain NGAS596]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=120904 DK92_RS06650 WP_002985680.1 1358924..1359925(-) (ccpA) [Streptococcus pyogenes strain NGAS596]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCCGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559