Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NMA510612_RS11195 Genome accession   NZ_CP007524
Coordinates   2134142..2134606 (-) Length   154 a.a.
NCBI ID   WP_010981060.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 510612     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2134142..2144659 2134142..2134606 within 0
IS/Tn 2132799..2133452 2134142..2134606 flank 690


Gene organization within MGE regions


Location: 2132799..2144659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMA510612_RS11185 (NMA510612_2482) - 2132799..2133452 (-) 654 WP_041423611.1 IS1595 family transposase -
  NMA510612_RS15260 - 2133572..2134030 (-) 459 WP_002234522.1 hypothetical protein -
  NMA510612_RS11195 (NMA510612_2484) comE 2134142..2134606 (-) 465 WP_010981060.1 ComEA family DNA-binding protein Machinery gene
  NMA510612_RS11230 (NMA510612_2490) - 2140406..2141212 (-) 807 WP_002245849.1 inner membrane protein YpjD -
  NMA510612_RS11235 (NMA510612_2491) ffh 2141433..2142803 (+) 1371 WP_002245848.1 signal recognition particle protein -
  NMA510612_RS11240 (NMA510612_2492) dsbA2 2143134..2143829 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  NMA510612_RS11245 (NMA510612_2493) - 2144000..2144659 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16529.75 Da        Isoelectric Point: 10.6993

>NTDB_id=120333 NMA510612_RS11195 WP_010981060.1 2134142..2134606(-) (comE) [Neisseria meningitidis strain 510612]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=120333 NMA510612_RS11195 WP_010981060.1 2134142..2134606(-) (comE) [Neisseria meningitidis strain 510612]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGTGCGCCCGCACCAAAAGGCCCAGCCAAACCAGTGCTGCCCGCGGATAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747

Multiple sequence alignment