Detailed information
Bioinformatically predicted
Overview
| Name | comE | Type | Machinery gene |
| Locus tag | NMA510612_RS01090 | Genome accession | NZ_CP007524 |
| Coordinates | 197794..198258 (-) | Length | 154 a.a. |
| NCBI ID | WP_010981060.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis strain 510612 | ||
| Function | DNA binding (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 178637..204476 | 197794..198258 | within | 0 |
Gene organization within MGE regions
Location: 178637..204476
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NMA510612_RS01005 (NMA510612_0205) | - | 178637..179467 (-) | 831 | WP_002215283.1 | DNA cytosine methyltransferase | - |
| NMA510612_RS01010 (NMA510612_0206) | - | 179498..181771 (-) | 2274 | WP_002239407.1 | Tex family protein | - |
| NMA510612_RS01015 (NMA510612_0207) | - | 181835..182485 (-) | 651 | WP_002218516.1 | ABC transporter ATP-binding protein | - |
| NMA510612_RS01020 (NMA510612_0208) | - | 182482..183279 (-) | 798 | WP_002236582.1 | ABC transporter permease | - |
| NMA510612_RS01025 (NMA510612_0209) | - | 183279..184442 (-) | 1164 | WP_002236581.1 | capsule polysaccharide export inner-membrane protein CtrB | - |
| NMA510612_RS01030 (NMA510612_0210) | ctrA | 184457..185620 (-) | 1164 | WP_002236580.1 | capsule polysaccharide export outer membrane protein CtrA | - |
| NMA510612_RS01035 (NMA510612_0211) | wecB | 185839..186957 (+) | 1119 | WP_002236579.1 | non-hydrolyzing UDP-N-acetylglucosamine 2-epimerase | - |
| NMA510612_RS01040 (NMA510612_0212) | - | 186959..188596 (+) | 1638 | WP_041423547.1 | stealth family protein | - |
| NMA510612_RS01045 (NMA510612_0213) | - | 188669..189412 (+) | 744 | WP_002236577.1 | YqiA/YcfP family alpha/beta fold hydrolase | - |
| NMA510612_RS01050 (NMA510612_0214) | - | 189414..190277 (+) | 864 | WP_002236576.1 | galactosyltransferase-related protein | - |
| NMA510612_RS01055 (NMA510612_0215) | galE | 190322..191341 (+) | 1020 | WP_002249569.1 | UDP-glucose 4-epimerase GalE | - |
| NMA510612_RS01060 (NMA510612_0216) | rfbB | 191457..192482 (+) | 1026 | WP_002236574.1 | dTDP-glucose 4,6-dehydratase | - |
| NMA510612_RS01065 (NMA510612_0217) | rfbA | 192588..193454 (+) | 867 | WP_002221803.1 | glucose-1-phosphate thymidylyltransferase RfbA | - |
| NMA510612_RS01070 (NMA510612_0218) | rfbC | 193508..194065 (+) | 558 | WP_002249566.1 | dTDP-4-dehydrorhamnose 3,5-epimerase | - |
| NMA510612_RS01075 (NMA510612_0219) | - | 194108..196126 (-) | 2019 | WP_002236572.1 | OPT family oligopeptide transporter | - |
| NMA510612_RS01080 (NMA510612_0221) | dnaJ | 196321..197442 (-) | 1122 | WP_002215274.1 | molecular chaperone DnaJ | - |
| NMA510612_RS14725 (NMA510612_0222) | - | 197524..197682 (-) | 159 | WP_002215272.1 | hypothetical protein | - |
| NMA510612_RS01090 (NMA510612_0223) | comE | 197794..198258 (-) | 465 | WP_010981060.1 | ComEA family DNA-binding protein | Machinery gene |
| NMA510612_RS01125 (NMA510612_0230) | dksA | 204060..204476 (-) | 417 | WP_002238569.1 | RNA polymerase-binding protein DksA | - |
Sequence
Protein
Download Length: 154 a.a. Molecular weight: 16529.75 Da Isoelectric Point: 10.6993
>NTDB_id=120293 NMA510612_RS01090 WP_010981060.1 197794..198258(-) (comE) [Neisseria meningitidis strain 510612]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
Nucleotide
Download Length: 465 bp
>NTDB_id=120293 NMA510612_RS01090 WP_010981060.1 197794..198258(-) (comE) [Neisseria meningitidis strain 510612]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGTGCGCCCGCACCAAAAGGCCCAGCCAAACCAGTGCTGCCCGCGGATAAAAAATAG
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGTGCGCCCGCACCAAAAGGCCCAGCCAAACCAGTGCTGCCCGCGGATAAAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comE | Neisseria gonorrhoeae MS11 |
94.262 |
79.221 |
0.747 |
| comE | Neisseria gonorrhoeae MS11 |
94.262 |
79.221 |
0.747 |
| comE | Neisseria gonorrhoeae MS11 |
94.262 |
79.221 |
0.747 |
| comE | Neisseria gonorrhoeae MS11 |
94.262 |
79.221 |
0.747 |