Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RP72_RS05185 Genome accession   NZ_CP010314
Coordinates   989293..989937 (+) Length   214 a.a.
NCBI ID   WP_003245647.1    Uniprot ID   O07528
Organism   Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet)     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 984293..994937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RP72_RS05170 (RP72_05170) glpD 984464..986131 (+) 1668 WP_003233382.1 glycerol-3-phosphate dehydrogenase -
  RP72_RS05175 (RP72_05175) pgcA 986263..988008 (+) 1746 WP_003244986.1 phosphoglucomutase -
  RP72_RS05180 (RP72_05180) yhcY 988157..989296 (+) 1140 WP_003245750.1 two-component system sensor histidine kinase YhcY -
  RP72_RS05185 (RP72_05185) vraR 989293..989937 (+) 645 WP_003245647.1 two-component system response regulator YhcZ Regulator
  RP72_RS05190 (RP72_05190) yhdA 989934..990458 (+) 525 WP_003244703.1 FMN-dependent NADPH-azoreductase -
  RP72_RS05195 (RP72_05195) yhdB 990473..990715 (-) 243 WP_003233373.1 YhdB family protein -
  RP72_RS05200 (RP72_05200) yhdC 990916..991239 (+) 324 WP_003233371.1 YqzG/YhdC family protein -
  RP72_RS05205 (RP72_05205) lytF 991281..992747 (-) 1467 WP_003244874.1 peptidoglycan endopeptidase LytF -
  RP72_RS05210 (RP72_05210) nsrR 992900..993340 (-) 441 WP_003245378.1 nitric oxide-sensing transcriptional repressor NsrR -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24022.59 Da        Isoelectric Point: 6.3034

>NTDB_id=119819 RP72_RS05185 WP_003245647.1 989293..989937(+) (vraR) [Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet)]
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=119819 RP72_RS05185 WP_003245647.1 989293..989937(+) (vraR) [Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet)]
ATGAAAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGA
AGTCGTCGGAGAAGCTGCAACTGGATTAGAAGCCCTCCGTGTCATCGAAGAGACAAAGCCGGATCTTGTGCTAATGGATT
TGTCTATGCCCGAGATGGACGGCATTCAAGCCATTAAAAAAGCAATACAGCAATTTCCGGATACGAATATCATTGTGCTG
ACGAGCTACTCTGATCAGGAGCACGTCATCCCCGCGCTTCAGGCAGGCGCGAAGGCGTATCAATTAAAGGATACGGAGCC
CGAGGAATTGGTGAAAACACGACAAGTGCATGGTGGCGAATACAAGCTTTCTACAGCTATTATGCCCCATGTGCTGACAC
ATATGAAAAATCAGCACGACCCGGAAAAAGAAAAATACTATCAATTAACTAGAAGGGAAAAAGACGTTCTGACTGAAATA
GCGAACGGGAAAAGCAATAAAGAAATCGCAGCAGCCTTGTTTATTTCAGAAAAAACAGTAAAAACCCATGTATCGAATCT
TTTAGCAAAACTTGAAGTGGCCGATCGCACGCAAGCAGCGCTTTTCGCAGTGAAATATAACCTGAATGGAGAGATCTCAA
AATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O07528

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

97.664

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

38.428

100

0.411

Multiple sequence alignment