Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   NTHI723_RS03335 Genome accession   NZ_CP007472
Coordinates   694911..695594 (-) Length   227 a.a.
NCBI ID   WP_011272301.1    Uniprot ID   Q4QLW8
Organism   Haemophilus influenzae strain 723     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 689911..700594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NTHI723_RS03320 (NTHI723_00670) nrdR 690716..691165 (-) 450 WP_005651549.1 transcriptional regulator NrdR -
  NTHI723_RS03325 (NTHI723_00671) recC 691220..694585 (-) 3366 WP_044364474.1 exodeoxyribonuclease V subunit gamma -
  NTHI723_RS03330 (NTHI723_00672) comQ 694631..694918 (-) 288 WP_021034778.1 DUF5374 domain-containing protein Machinery gene
  NTHI723_RS03335 (NTHI723_00673) comP 694911..695594 (-) 684 WP_011272301.1 DUF2572 family protein Machinery gene
  NTHI723_RS03340 (NTHI723_00674) comO 695591..696310 (-) 720 WP_011272300.1 type II secretion system protein J Machinery gene
  NTHI723_RS03345 (NTHI723_00675) comN 696310..696822 (-) 513 WP_011272299.1 type II secretion system protein Machinery gene
  NTHI723_RS03350 (NTHI723_00676) suhB 697022..697834 (+) 813 WP_011272298.1 inositol-1-monophosphatase -
  NTHI723_RS03355 (NTHI723_00677) nrfE 697943..699850 (+) 1908 WP_011272297.1 heme lyase NrfEFG subunit NrfE -
  NTHI723_RS03360 (NTHI723_00678) - 699850..700380 (+) 531 WP_005688388.1 DsbE family thiol:disulfide interchange protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 25371.21 Da        Isoelectric Point: 9.5157

>NTDB_id=119762 NTHI723_RS03335 WP_011272301.1 694911..695594(-) (comP) [Haemophilus influenzae strain 723]
MTIQKGIITLTILIFISGLLSVILLLDDSNLSFFRAQQNQRKLYVERTLQLQRITALKKQTACLDLSLNNDESVKQISIT
LDGATDSIQYFLWCERMSLFKKSPKKGDNQGALKDFVSGEKLAYFRPHFSSPPRILNANKTPKLYWFSDSQAEVEINGTV
SAVLIAEGDLKLTGKGRISGAVITNGNLTLDGVTLAYGKKTVVALVQQYSQWKLAEKSWSDFNVQDE

Nucleotide


Download         Length: 684 bp        

>NTDB_id=119762 NTHI723_RS03335 WP_011272301.1 694911..695594(-) (comP) [Haemophilus influenzae strain 723]
ATGACAATACAAAAAGGTATTATTACGCTGACTATTCTGATTTTTATTTCAGGCTTATTAAGCGTAATCTTATTGTTAGA
TGATAGCAATTTAAGTTTTTTTCGGGCGCAACAAAATCAACGAAAACTGTATGTGGAAAGAACATTACAATTACAAAGAA
TAACAGCCTTGAAAAAACAAACTGCCTGCCTTGATTTATCATTAAATAATGATGAAAGTGTAAAGCAAATCAGCATTACG
CTTGATGGTGCCACAGATTCAATTCAATATTTTCTTTGGTGTGAAAGAATGAGCCTATTTAAAAAATCGCCTAAAAAGGG
AGATAATCAAGGCGCATTGAAAGATTTTGTGAGTGGCGAAAAACTTGCCTATTTTCGACCGCACTTTTCTTCTCCGCCCA
GAATTTTAAACGCGAATAAAACGCCTAAACTTTATTGGTTTTCAGATTCACAAGCAGAGGTTGAAATTAATGGCACGGTG
TCTGCCGTATTAATTGCAGAGGGCGATTTAAAATTGACTGGCAAAGGGAGGATTAGTGGCGCAGTGATTACCAACGGGAA
TTTAACTTTAGATGGCGTAACTTTAGCTTATGGGAAAAAGACGGTGGTCGCTTTAGTGCAACAATATAGTCAGTGGAAGT
TAGCAGAAAAAAGTTGGAGTGATTTTAATGTTCAGGATGAATAA

Domains

Predicted by InterproScan.

Protein of unknown function (DUF2572) (DUF2572)

(5-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Haemophilus influenzae Rd KW20

91.63

100

0.916

Multiple sequence alignment