Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE1/comEA   Type   Machinery gene
Locus tag   NTHI477_RS03455 Genome accession   NZ_CP007470
Coordinates   724984..725331 (-) Length   115 a.a.
NCBI ID   WP_044330715.1    Uniprot ID   A0A2S9RQZ5
Organism   Haemophilus influenzae strain 477     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 719984..730331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NTHI477_RS03435 (NTHI477_00699) bioB 720373..721374 (-) 1002 WP_044330706.1 biotin synthase BioB -
  NTHI477_RS03440 (NTHI477_00700) thiQ 721487..722134 (-) 648 WP_014550963.1 thiamine ABC transporter ATP-binding protein -
  NTHI477_RS03445 (NTHI477_00701) thiP 722118..723734 (-) 1617 WP_044330709.1 thiamine/thiamine pyrophosphate ABC transporter permease -
  NTHI477_RS03450 (NTHI477_00702) thiB 723739..724737 (-) 999 WP_044330712.1 thiamine ABC transporter substrate binding subunit -
  NTHI477_RS03455 (NTHI477_00703) comE1/comEA 724984..725331 (-) 348 WP_044330715.1 helix-hairpin-helix domain-containing protein Machinery gene
  NTHI477_RS03460 (NTHI477_00704) ispH 725500..726444 (-) 945 WP_044330718.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
  NTHI477_RS03465 (NTHI477_00705) lspA 726441..726956 (-) 516 WP_044330721.1 signal peptidase II -
  NTHI477_RS03470 (NTHI477_00706) - 727026..728585 (-) 1560 WP_044330724.1 phosphoethanolamine transferase -

Sequence

Protein


Download         Length: 115 a.a.        Molecular weight: 12481.31 Da        Isoelectric Point: 6.9796

>NTDB_id=119688 NTHI477_RS03455 WP_044330715.1 724984..725331(-) (comE1/comEA) [Haemophilus influenzae strain 477]
MKLMKTLFTSFVLCGSLAAGSTFAEDNVVEQTTQAVVTTQTDSQVAPAMMGDKLNINTATVSEIQKSLTGIGAKKAEAIV
QYREKHGNFTNVEQLLEVQGIGKATLEKNRDRIIF

Nucleotide


Download         Length: 348 bp        

>NTDB_id=119688 NTHI477_RS03455 WP_044330715.1 724984..725331(-) (comE1/comEA) [Haemophilus influenzae strain 477]
ATGAAATTAATGAAAACATTATTCACTTCGTTTGTATTGTGTGGGTCACTTGCAGCTGGTTCCACTTTTGCTGAAGACAA
TGTGGTTGAGCAAACAACTCAAGCTGTTGTGACCACTCAAACGGATTCACAAGTAGCACCAGCTATGATGGGAGATAAAT
TGAATATTAACACAGCAACTGTGAGTGAAATTCAAAAATCTCTAACAGGAATTGGTGCGAAAAAAGCAGAAGCGATAGTG
CAATATCGTGAAAAACACGGTAATTTTACTAATGTAGAACAGCTTTTAGAAGTACAAGGAATTGGCAAAGCAACACTAGA
AAAAAATCGTGATCGTATAATCTTTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(52-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S9RQZ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE1/comEA Haemophilus influenzae Rd KW20

80.357

97.391

0.783
  comEA/comE1 Glaesserella parasuis strain SC1401

57.009

93.043

0.53

Multiple sequence alignment