Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   CH52_RS03060 Genome accession   NZ_CP007454
Coordinates   591093..591662 (-) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain 502A isolate RN6607     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 586093..596662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH52_RS03025 (CH52_03050) - 586567..587175 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  CH52_RS03030 (CH52_03055) rplL 587350..587718 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  CH52_RS03035 (CH52_03060) rplJ 587761..588261 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  CH52_RS03040 (CH52_03065) rplA 588533..589225 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  CH52_RS03045 (CH52_03070) rplK 589433..589855 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  CH52_RS03050 (CH52_03075) nusG 590036..590584 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  CH52_RS03055 (CH52_03080) secE 590597..590779 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  CH52_RS14340 rpmG 590835..590978 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  CH52_RS03060 (CH52_03085) sigH 591093..591662 (-) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  CH52_RS03065 (CH52_03090) - 591743..592267 (-) 525 WP_000664737.1 NYN domain-containing protein -
  CH52_RS03070 (CH52_03095) rlmB 592267..593013 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  CH52_RS03075 (CH52_03100) - 593021..593425 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  CH52_RS03080 (CH52_03105) cysS 593418..594818 (-) 1401 WP_000631969.1 cysteine--tRNA ligase -
  CH52_RS03085 (CH52_03110) cysE 594802..595449 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=119480 CH52_RS03060 WP_000872882.1 591093..591662(-) (sigH) [Staphylococcus aureus strain 502A isolate RN6607]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=119480 CH52_RS03060 WP_000872882.1 591093..591662(-) (sigH) [Staphylococcus aureus strain 502A isolate RN6607]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment