Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   DYB47_RS05980 Genome accession   NZ_UHFV01000002
Coordinates   1179585..1180454 (+) Length   289 a.a.
NCBI ID   WP_003081678.1    Uniprot ID   G5JUM1
Organism   Streptococcus macacae NCTC 11558     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1174585..1185454
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS05965 (NCTC11558_01203) lepA 1174757..1176592 (-) 1836 WP_003079907.1 translation elongation factor 4 -
  DYB47_RS05970 (NCTC11558_01204) - 1176863..1178716 (-) 1854 WP_003082157.1 GbpC/Spa domain-containing protein -
  DYB47_RS05975 (NCTC11558_01205) - 1178957..1179208 (-) 252 WP_040841519.1 helix-turn-helix domain-containing protein -
  DYB47_RS05980 (NCTC11558_01206) irvR 1179585..1180454 (+) 870 WP_003081678.1 XRE family transcriptional regulator Regulator
  DYB47_RS05985 (NCTC11558_01220) - 1181550..1181930 (-) 381 WP_003081342.1 type II toxin-antitoxin system HicB family antitoxin -
  DYB47_RS05990 (NCTC11558_01221) - 1181947..1182138 (-) 192 WP_003078721.1 type II toxin-antitoxin system HicA family toxin -
  DYB47_RS05995 (NCTC11558_01222) csn2 1182236..1182898 (-) 663 WP_003080535.1 type II-A CRISPR-associated protein Csn2 -
  DYB47_RS06000 (NCTC11558_01223) cas2 1182888..1183232 (-) 345 WP_040841521.1 CRISPR-associated endonuclease Cas2 -
  DYB47_RS06005 (NCTC11558_01224) cas1 1183229..1184098 (-) 870 WP_003081945.1 type II CRISPR-associated endonuclease Cas1 -

Sequence

Protein


Download         Length: 289 a.a.        Molecular weight: 32651.47 Da        Isoelectric Point: 9.4965

>NTDB_id=1171321 DYB47_RS05980 WP_003081678.1 1179585..1180454(+) (irvR) [Streptococcus macacae NCTC 11558]
MGRGKLTPQDKKDMKIISANLQGLLDEYEITQSHLATLLKIPKSSLNEYVKGKSLPKAGNVQKLADYFGLKKSDIDPRFS
TKTTSFAVEKISNISRQLESKRQKKVLAFCQQQLADQKETAAVKNKPSDNAKADYQKAVETFIAKELEDQNRIDLNNIKK
VKDLYQALGHKYEDVILYGEVSAGTGVWVGHEKAETIQYPAPIPEHDIALRVNGNSMEPLFYDGDLIFVKKTKTIHHGQI
IVAIVNNEAYVKKFYRKNKEIRLISLNPDYNDIILKENDTIDIIGTVIT

Nucleotide


Download         Length: 870 bp        

>NTDB_id=1171321 DYB47_RS05980 WP_003081678.1 1179585..1180454(+) (irvR) [Streptococcus macacae NCTC 11558]
ATGGGACGTGGAAAACTAACACCACAAGATAAAAAAGATATGAAGATTATTTCAGCTAACCTTCAAGGACTTCTTGACGA
GTATGAAATAACACAATCACACTTAGCAACTTTATTAAAGATACCTAAAAGCAGTTTAAATGAATATGTCAAAGGAAAAA
GCCTGCCTAAAGCCGGAAATGTTCAAAAGCTTGCCGATTACTTTGGCCTGAAAAAATCCGATATAGATCCAAGATTCTCA
ACCAAAACAACTTCTTTCGCAGTTGAAAAGATTAGCAATATTAGCAGACAATTAGAAAGTAAACGGCAAAAGAAAGTTCT
TGCCTTCTGTCAGCAGCAACTAGCAGATCAAAAAGAGACAGCAGCTGTAAAAAACAAACCGTCTGATAATGCTAAAGCAG
ACTATCAAAAGGCTGTTGAGACATTTATTGCTAAAGAATTAGAAGATCAAAATAGGATTGATCTCAATAATATCAAAAAA
GTCAAAGACTTGTATCAGGCTTTAGGCCACAAGTATGAAGATGTGATACTTTACGGTGAAGTATCTGCTGGAACAGGTGT
TTGGGTAGGGCATGAAAAAGCAGAAACGATTCAGTATCCAGCACCAATACCAGAACACGACATTGCTCTTAGGGTCAATG
GCAATAGTATGGAACCCTTATTTTACGATGGTGATCTCATCTTCGTTAAAAAAACTAAAACGATTCATCACGGGCAAATT
ATCGTCGCTATTGTAAATAATGAAGCATATGTCAAAAAATTTTATCGCAAAAATAAAGAAATAAGACTTATTTCGCTCAA
TCCCGATTATAACGACATTATCTTAAAGGAAAATGATACTATTGACATTATCGGAACTGTTATCACTTAA

Domains

Predicted by InterproScan.

Peptidase S24-like (Peptidase_S24)

(177-288)

Helix-turn-helix (HTH_3)

(26-71)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JUM1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

69.697

100

0.716

Multiple sequence alignment