Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACLV7W_RS09350 Genome accession   NZ_OZ217346
Coordinates   1924097..1924786 (-) Length   229 a.a.
NCBI ID   WP_261053407.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis D22     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1919097..1929786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS09330 (SMID22_19230) mvaD 1920011..1920964 (-) 954 WP_411865845.1 diphosphomevalonate decarboxylase -
  ACLV7W_RS09335 (SMID22_19240) mvk 1920946..1921824 (-) 879 WP_033682285.1 mevalonate kinase -
  ACLV7W_RS09340 (SMID22_19250) cbpF 1921947..1922969 (-) 1023 WP_033682286.1 choline-binding protein CbpF -
  ACLV7W_RS09345 (SMID22_19260) cbpJ 1922987..1923997 (-) 1011 WP_411865846.1 choline-binding protein CbpJ -
  ACLV7W_RS09350 (SMID22_19270) covR 1924097..1924786 (-) 690 WP_261053407.1 response regulator transcription factor Regulator
  ACLV7W_RS09355 (SMID22_19280) gndA 1924798..1926222 (-) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  ACLV7W_RS09360 (SMID22_19290) mapZ 1926298..1927704 (-) 1407 WP_411865847.1 cell division site-positioning protein MapZ -
  ACLV7W_RS09365 (SMID22_19300) - 1927718..1928875 (-) 1158 WP_411865848.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  ACLV7W_RS09375 (SMID22_19330) gpsB 1929361..1929690 (-) 330 WP_191962423.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26806.88 Da        Isoelectric Point: 7.3520

>NTDB_id=1170460 ACLV7W_RS09350 WP_261053407.1 1924097..1924786(-) (covR) [Streptococcus mitis isolate S. mitis D22]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNARLGDMTAQDFADKLSRTKPASVIMVL
DNREELQDQIETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIDLTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1170460 ACLV7W_RS09350 WP_261053407.1 1924097..1924786(-) (covR) [Streptococcus mitis isolate S. mitis D22]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCGTCTGGGGGATATGACAGCCCAGGATTTTGCAGACAAGCTGAGTCGGACTAAGCCAGCCTCAGTGATCATGGTCTTG
GACAATCGCGAAGAATTGCAAGATCAGATTGAGACAATCCAACGCTTTGCCGTTTCTTACATCTATAAGCCGGTTATTAT
TGACAATTTGGTGGCTCGTATTTCAGCAATTTTCCGAGGTAGGGACTTCATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACGTCTTACCGTAATCTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGATCTGACCCGT
CGTGAGTATGACCTTTTGGCTACTCTTATGGGAAGCAAGAAAGTTCTGACTCGTGAGCAGTTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAAACAAATATCGTGGATGTCTACATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACAGTACGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment