Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACLV7D_RS08645 Genome accession   NZ_OZ217345
Coordinates   1807097..1807786 (-) Length   229 a.a.
NCBI ID   WP_050283620.1    Uniprot ID   A0A1E9GD25
Organism   Streptococcus mitis isolate S. mitis F22     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1802097..1812786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7D_RS08635 (SMIF22_17120) - 1804476..1805642 (+) 1167 WP_411865964.1 IS30 family transposase -
  ACLV7D_RS08640 (SMIF22_17130) - 1806081..1806977 (-) 897 WP_411865965.1 N-acetylmuramoyl-L-alanine amidase family protein -
  ACLV7D_RS08645 (SMIF22_17140) covR 1807097..1807786 (-) 690 WP_050283620.1 response regulator transcription factor Regulator
  ACLV7D_RS08650 (SMIF22_17150) gndA 1807798..1809222 (-) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  ACLV7D_RS08655 (SMIF22_17160) mapZ 1809298..1810704 (-) 1407 WP_218764843.1 cell division site-positioning protein MapZ -
  ACLV7D_RS08660 (SMIF22_17170) - 1810717..1811874 (-) 1158 WP_000711397.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  ACLV7D_RS08670 (SMIF22_17200) gpsB 1812360..1812701 (-) 342 WP_000146532.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26766.86 Da        Isoelectric Point: 7.4648

>NTDB_id=1170388 ACLV7D_RS08645 WP_050283620.1 1807097..1807786(-) (covR) [Streptococcus mitis isolate S. mitis F22]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1170388 ACLV7D_RS08645 WP_050283620.1 1807097..1807786(-) (covR) [Streptococcus mitis isolate S. mitis F22]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCATCTGGGGGATATGACAGCCCAGGATTTTGCAGATAAGCTGAGTCGGACTAAGCCAGCCTCAGTCATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGATCAGATTGAGACAATCCAACGCTTTGCCGTTTCTTACATCTATAAGCCAGTTATTAT
TGACAATTTGGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACGTCTTACCGCAATCTGCGTATGGATGTAGAACATCATACTGTTTATCGTGGCGAGGAGATGATTGCTCTGACCCGT
CGTGAGTATGACCTTTTGGCTACTCTTATGGGAAGCAAGAAAGTTCTGACTCGTGAGCAGTTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAAACTAATATCGTGGATGTCTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E9GD25

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment