Detailed information NTG1170305

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: ACLV7A_RS08320
• Genome accession: NZ_OZ217344
• Coordinates: 1724486..1725175 (-)
• Length: 229 a.a.
• NCBI ID: WP_368081757.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis E22
• Function: repress comR expression (predicted from homology) Competence regulation

Genomic Context

Location: 1719486..1730175

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7A_RS08315 (SMIE22_16470)	-	1723470..1724387 (-)	918	WP_411864077.1	N-acetylmuramoyl-L-alanine amidase family protein	-
ACLV7A_RS08320 (SMIE22_16480)	covR	1724486..1725175 (-)	690	WP_368081757.1	response regulator transcription factor	Regulator
ACLV7A_RS08325 (SMIE22_16490)	gndA	1725187..1726611 (-)	1425	WP_050252407.1	NADP-dependent phosphogluconate dehydrogenase	-
ACLV7A_RS08330 (SMIE22_16500)	mapZ	1726687..1728084 (-)	1398	WP_411864078.1	cell division site-positioning protein MapZ	-
ACLV7A_RS08335 (SMIE22_16510)	-	1728097..1729254 (-)	1158	WP_411864079.1	THUMP domain-containing class I SAM-dependent RNA methyltransferase	-
ACLV7A_RS08345 (SMIE22_16540)	gpsB	1729741..1730082 (-)	342	WP_000200644.1	cell division regulator GpsB	-

Sequence

Protein

• Length: 229 a.a.
• Molecular weight: 26770.85 Da
• Isoelectric Point: 7.4648

>NTDB_id=1170305 ACLV7A_RS08320 WP_368081757.1 1724486..1725175(-) (covR) [Streptococcus mitis isolate S. mitis E22]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKSASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIENLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide

• Length: 690 bp

>NTDB_id=1170305 ACLV7A_RS08320 WP_368081757.1 1724486..1725175(-) (covR) [Streptococcus mitis isolate S. mitis E22]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCATCTGGGGGATATGACAGCCCAGGATTTTGCAGACAAGCTGAGTCGGACTAAGTCAGCCTCGGTCATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGATCAGATTGAAACAATCCAACGCTTTGCCGTTTCTTACATCTATAAGCCGGTTATTAT
TGAGAATCTGGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGATCAACACTGCAGTCAGATGAAGGTTC
CAACGTCTTACCGAAATCTGCGTATGGATGTAGAACATCATACTGTTTATCGTGGCGAGGAGATGATTGCCCTGACCCGT
CGTGAGTATGACCTTTTGGCTACTCTTATGGGAAGCAAGAAAGTTCTGACTCGTGAGCAGTTATTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAGACTAATATCGTGGATGTCTATATCCGCTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTTCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (154-226)

• Response regulator receiver domain (Response_reg) (5-114)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Streptococcus salivarius strain HSISS4	49.13	100	0.493
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.93	99.563	0.467