Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   ACLV7A_RS05725 Genome accession   NZ_OZ217344
Coordinates   1172504..1174306 (-) Length   600 a.a.
NCBI ID   WP_411863832.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis E22     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1167504..1179306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7A_RS05690 (SMIE22_11260) - 1167990..1168832 (+) 843 WP_411863828.1 DUF368 domain-containing protein -
  ACLV7A_RS05695 (SMIE22_11270) - 1168832..1169314 (+) 483 WP_411863829.1 aminoacyl-tRNA deacylase -
  ACLV7A_RS05700 (SMIE22_11280) - 1169314..1169934 (+) 621 WP_000780816.1 histidine phosphatase family protein -
  ACLV7A_RS05705 - 1170213..1170371 (-) 159 WP_025173180.1 hypothetical protein -
  ACLV7A_RS05710 - 1170383..1170478 (-) 96 Protein_1082 IS630 family transposase -
  ACLV7A_RS05715 (SMIE22_11290) prsA 1170784..1171722 (-) 939 WP_411863830.1 peptidylprolyl isomerase PrsA -
  ACLV7A_RS05720 (SMIE22_11300) - 1171789..1172502 (-) 714 WP_411863831.1 O-methyltransferase -
  ACLV7A_RS05725 (SMIE22_11310) pepF 1172504..1174306 (-) 1803 WP_411863832.1 oligoendopeptidase F Regulator
  ACLV7A_RS05730 (SMIE22_11320) coiA 1174325..1175278 (-) 954 WP_411863833.1 competence protein CoiA Machinery gene
  ACLV7A_RS05735 (SMIE22_11330) tehB 1175351..1176211 (-) 861 WP_411863834.1 SAM-dependent methyltransferase TehB -
  ACLV7A_RS05740 (SMIE22_11340) smpB 1176227..1176694 (-) 468 WP_001051750.1 SsrA-binding protein SmpB -
  ACLV7A_RS05745 (SMIE22_11350) rnr 1176657..1179011 (-) 2355 WP_411863835.1 ribonuclease R -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69937.76 Da        Isoelectric Point: 4.5080

>NTDB_id=1170290 ACLV7A_RS05725 WP_411863832.1 1172504..1174306(-) (pepF) [Streptococcus mitis isolate S. mitis E22]
MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQTEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLDQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKNREVRRGAYQALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAVNFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALK
KAEEALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDETRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=1170290 ACLV7A_RS05725 WP_411863832.1 1172504..1174306(-) (pepF) [Streptococcus mitis isolate S. mitis E22]
ATGGTATTACAAAGAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATTTACCCAACTGACCAGGCTTGGGA
AGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTATTGGATAGTGCGGATAACC
TACTCGAAATTACTGAATTTTCTCTTGAAATGGAACGACAGACAGAGAAGCTTTACGTTTATGCTCATATGAAGAATGAC
CAAGACACACGTGAAGCCAAGTATCAAGAGTACTATGCCAAGGCTATGACTCTCTATAGTCAGCTAGACCAAGCCTTTTC
ATTCTATGAACCTGAATTTATGGAAATTAGTGAAAAGCAGTATGCTGACTTTTTAGAGGCTCAACCAAAATTGCAGGTTT
ATCAACACTATTTTGACAAGCTCTTGCAAGGCAAGGATCACGTTCTTTCACAACGCGAAGAAGAATTATTAGCTGGAGCT
GGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATTTTGGACAATGCGGATATTGTGTTCCCTTATGTCCTCGACGA
TGATGGTAAGGAAGTGCAGCTCTCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAACCGTGAGGTTCGTCGTGGTG
CCTATCAAGCCCTCTATGCGACTTATGAGCAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTTAAGGTTCAA
AACTATCGTGCAAAAGTTCGCAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGTAAATTTTGTTCCAGAGAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGCAAGCACTTGCCACTCTTGCATCGTTACCTTGAACTTCGTTCAAAAATCTTGGGAA
TTTCAGACCTCAAGATGTACGATGTCTACACACCGCTTTCGTCTGTTGAATATAGTTTTACCTACCAAGAAGCTTTGAAA
AAAGCAGAAGAAGCCTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTTAAACGTGCCTTTAGTGAGCGTTGGATTGA
TGTTTACGAAAATCAAGGCAAGCGTTCAGGAGCCTACTCTGGCGGTTCTTACGATACCAATGCCTTTATGCTCCTAAACT
GGCAGGACAACCTAGATAATCTCTTTACCCTTGTCCATGAGACTGGTCACAGTATGCACTCAAGCTATACTCGTGAAACT
CAGCCTTATGTTTACGGAGATTATTCTATCTTCTTGGCTGAGATTGCCTCAACGACCAATGAAAATATCTTGACGGAGAA
ATTATTGGAAGAAGTGGAAGACGACGAAACGCGCTTTGCTATTCTTAATAACTTCCTAGACGGTTTCCGAGGAACAGTTT
TTCGTCAAACTCAATTTGCTGAGTTTGAACACGCTATCCACCAAGCGGACCAAAATGGAGAAGTCTTGACAAGCGATTTC
CTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGATTGAGCAAGGAAGACAATCCTGAAATCCAATACGAGTG
GGCACGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACAGGCTTTGCAGCAGCCTCAGCCTTGGCTG
AAAAGATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAATCTGACTATCCACTT
AATGTCATGAGAAAAGCTGGAGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGAACGTCGTTT
GAATGAGTTTGAAGCCCTTGTTGAAAAATTGGGATTGGCATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(112-181)

Peptidase family M3 (Peptidase_M3)

(202-581)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.45

99.333

0.67

Multiple sequence alignment