Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACLV7Z_RS09005 Genome accession   NZ_OZ217343
Coordinates   1815190..1815879 (-) Length   229 a.a.
NCBI ID   WP_218774094.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis G22     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1810190..1820879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Z_RS08990 (SMIG22_17720) cbpF 1812772..1813794 (-) 1023 WP_218774095.1 choline-binding protein CbpF -
  ACLV7Z_RS08995 - 1813813..1813941 (-) 129 WP_397634592.1 hypothetical protein -
  ACLV7Z_RS09000 (SMIG22_17730) - 1813939..1815078 (-) 1140 Protein_1727 trypsin-like peptidase domain-containing protein -
  ACLV7Z_RS09005 (SMIG22_17740) covR 1815190..1815879 (-) 690 WP_218774094.1 response regulator transcription factor Regulator
  ACLV7Z_RS09010 (SMIG22_17750) gndA 1815891..1817315 (-) 1425 WP_218774093.1 NADP-dependent phosphogluconate dehydrogenase -
  ACLV7Z_RS09015 (SMIG22_17760) mapZ 1817391..1818797 (-) 1407 WP_218774092.1 cell division site-positioning protein MapZ -
  ACLV7Z_RS09020 (SMIG22_17770) - 1818810..1819967 (-) 1158 WP_218774091.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  ACLV7Z_RS09030 (SMIG22_17800) gpsB 1820453..1820794 (-) 342 WP_000146532.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26801.90 Da        Isoelectric Point: 8.0259

>NTDB_id=1170227 ACLV7Z_RS09005 WP_218774094.1 1815190..1815879(-) (covR) [Streptococcus mitis isolate S. mitis G22]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNARLGDMTAQDFADKLSRTKPSSVIMVL
DHREELQDQLETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1170227 ACLV7Z_RS09005 WP_218774094.1 1815190..1815879(-) (covR) [Streptococcus mitis isolate S. mitis G22]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAAAGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTGGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCGTCTGGGGGATATGACAGCCCAGGATTTTGCAGACAAGCTGAGTCGGACTAAGCCATCCTCAGTCATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGCTTGAGACAATCCAACGCTTTGCCGTTTCTTACATCTATAAGCCAGTAATCAT
TGATAATTTGGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACGTCTTACCGTAATCTGCGTATGGATGTAGAGCATCATACCGTTTATCGTGGCGAAGAGATGATTGCTCTGACTCGT
CGTGAGTATGACCTTTTGGCTACTCTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGCTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGTAGCAAGCTGGATGTAAAAGGTCAGA
AAAGCTATATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment