Detailed information NTG1170179

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ACLV7Z_RS01585
• Genome accession: NZ_OZ217343
• Coordinates: 297692..298729 (+)
• Length: 345 a.a.
• NCBI ID: WP_218774534.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis G22
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 292692..303729

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7Z_RS01555 (SMIG22_03030)	-	293629..293907 (-)	279	WP_001174613.1	acylphosphatase	-
ACLV7Z_RS01560 (SMIG22_03040)	-	293941..294681 (+)	741	WP_218774530.1	TrmH family RNA methyltransferase	-
ACLV7Z_RS01565 (SMIG22_03050)	-	294737..295420 (+)	684	WP_001016914.1	Bax inhibitor-1/YccA family protein	-
ACLV7Z_RS01570 (SMIG22_03060)	asnA	295531..296523 (+)	993	WP_218774531.1	aspartate--ammonia ligase	-
ACLV7Z_RS01575 (SMIG22_03070)	rsmD	296691..297230 (+)	540	WP_218774532.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACLV7Z_RS01580 (SMIG22_03080)	coaD	297220..297708 (+)	489	WP_218774533.1	pantetheine-phosphate adenylyltransferase	-
ACLV7Z_RS01585 (SMIG22_03090)	sepM	297692..298729 (+)	1038	WP_218774534.1	SepM family pheromone-processing serine protease	Regulator
ACLV7Z_RS01590 (SMIG22_03100)	-	298787..299017 (+)	231	WP_078135418.1	DUF1146 family protein	-
ACLV7Z_RS01595 (SMIG22_03110)	murA	299041..300324 (+)	1284	WP_218774535.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ACLV7Z_RS01600 (SMIG22_03120)	-	300317..300505 (+)	189	WP_218774536.1	DNA-directed RNA polymerase subunit beta	-
ACLV7Z_RS01605 (SMIG22_03130)	endA	300544..301368 (+)	825	WP_218774537.1	DNA/RNA non-specific endonuclease	Machinery gene
ACLV7Z_RS01610 (SMIG22_03140)	-	301518..302849 (+)	1332	WP_218774538.1	hemolysin family protein	-
ACLV7Z_RS01615	-	302911..303045 (+)	135	WP_259390846.1	hypothetical protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37432.40 Da
• Isoelectric Point: 5.2054

>NTDB_id=1170179 ACLV7Z_RS01585 WP_218774534.1 297692..298729(+) (sepM) [Streptococcus mitis isolate S. mitis G22]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDQAAGAYHFVTVGVQHATLAHMVYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQQLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPGLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARSGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=1170179 ACLV7Z_RS01585 WP_218774534.1 297692..298729(+) (sepM) [Streptococcus mitis isolate S. mitis G22]
ATGAAAAAAAAGATTAGATGGCCCTTATATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATCAGGCGGCTG
GTGCCTATCACTTTGTTACGGTTGGTGTCCAGCATGCCACATTGGCTCATATGGTTTATGCTTGGTTGACGCCTTTTACA
GATATTCGTAGTGCTCAAGAGACTACAGGTGGCTCTTCCGATGTAGAATTTATGCGGATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGTCTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGGGTTTATGTCT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACATTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAACAATTAGGGGACTCCGTTAAGGTCACCTATGAAGAGGATGG
GCAAACCAAATCTGCAGAAGGTAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGTTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGGTCTTCGTAATGGTCGTATTGTTGCCGGTACAGGAACCATTGACCGTGATGG
CAATGTGGGGGATATTGGTGGTATTGACAAGAAAGTTGTAGCTTCTGCTAGGTCAGGTGCCGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAAGCGCATCCTGATGCTAAAAACAACTACCAAACAGCCCTAGAAGCGGCCAAA
ACAATCAAGACAGATATGAAAATCGTGCCTGTTAAAACCCTACAAGATGCAATTGATTACTTGAAAAACAATCCCTAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (231-296)

• PDZ domain (PDZ_2) (130-193)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	58.48	99.13	0.58