Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   ACLV7Z_RS01605 Genome accession   NZ_OZ217343
Coordinates   300544..301368 (+) Length   274 a.a.
NCBI ID   WP_218774537.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis G22     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 295544..306368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Z_RS01575 (SMIG22_03070) rsmD 296691..297230 (+) 540 WP_218774532.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ACLV7Z_RS01580 (SMIG22_03080) coaD 297220..297708 (+) 489 WP_218774533.1 pantetheine-phosphate adenylyltransferase -
  ACLV7Z_RS01585 (SMIG22_03090) sepM 297692..298729 (+) 1038 WP_218774534.1 SepM family pheromone-processing serine protease Regulator
  ACLV7Z_RS01590 (SMIG22_03100) - 298787..299017 (+) 231 WP_078135418.1 DUF1146 family protein -
  ACLV7Z_RS01595 (SMIG22_03110) murA 299041..300324 (+) 1284 WP_218774535.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ACLV7Z_RS01600 (SMIG22_03120) - 300317..300505 (+) 189 WP_218774536.1 DNA-directed RNA polymerase subunit beta -
  ACLV7Z_RS01605 (SMIG22_03130) endA 300544..301368 (+) 825 WP_218774537.1 DNA/RNA non-specific endonuclease Machinery gene
  ACLV7Z_RS01610 (SMIG22_03140) - 301518..302849 (+) 1332 WP_218774538.1 hemolysin family protein -
  ACLV7Z_RS01615 - 302911..303045 (+) 135 WP_259390846.1 hypothetical protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29886.39 Da        Isoelectric Point: 9.7812

>NTDB_id=1170180 ACLV7Z_RS01605 WP_218774537.1 300544..301368(+) (endA) [Streptococcus mitis isolate S. mitis G22]
MNKKTRQTLIGLLVLLILSAGSYYIKQNELGNQAAKTKISQKSQSPDAPSQELAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=1170180 ACLV7Z_RS01605 WP_218774537.1 300544..301368(+) (endA) [Streptococcus mitis isolate S. mitis G22]
ATGAACAAAAAAACAAGACAGACACTGATTGGCTTGCTAGTGTTATTGATCTTATCTGCGGGGAGCTATTATATTAAGCA
GAATGAACTAGGCAATCAGGCTGCTAAGACAAAAATAAGTCAGAAAAGTCAATCACCAGACGCGCCTAGTCAAGAATTGG
CGGAAAGTGTCTTAACAGATGCAGTCAAGAGTCAAATAAAAGGGAGTCTGGAGTGGAATGGATCCGGTGCTTTTATCGTC
AATGGCAATAAAACAAATCTAGATGCTAAGGTTTCAAGTAAGCCCTACGCTGATAATAAAACAAAGACAGTGGGCAAGGA
AACGGTACCAACCGTAGCTAATGCCCTCTTGTCTAAGGCTACTCGTCAGTACAAGAATCGTGAAGAAACTGGGAATGGTT
CGACTTCATGGACTCCTCCAGGCTGGCATCAGGTTAAGAATCTAAAGGGTACTTATACCCATGCGGTCGATAGAGGTCAC
TTGTTAGGCTATGCCTTAATCGGTGGCTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGGATTCGACTGGTCAAAACTACTATGAAAGTAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTTCGTTACCGTGTAACCCTTTATTATGCTTCAAACGAGGATTTAGTTCCTTCAGCTTCACAGATTGAA
GCCAAGTCTTCAGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAAGGGCTTCAACTGGATTACCGCAC
TGGAGAAGTAACTGTAACCCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

92.701

100

0.927
  endA Streptococcus pneumoniae D39

92.701

100

0.927
  endA Streptococcus pneumoniae R6

92.701

100

0.927
  endA Streptococcus pneumoniae TIGR4

92.701

100

0.927

Multiple sequence alignment